Detailed information NTG1137847

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DQM48_RS10050
• Genome accession: NZ_LS483348
• Coordinates: 1964278..1965528 (+)
• Length: 416 a.a.
• NCBI ID: WP_020917669.1
• Uniprot ID: A0AB33APT2
• Organism: Streptococcus lutetiensis strain NCTC8738
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1959278..1970528

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM48_RS10025	-	1961384..1962746 (+)	1363	Protein_1929	IS3 family transposase	-
DQM48_RS10045 (NCTC8738_02127)	rlmH	1963584..1964063 (-)	480	WP_020917668.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DQM48_RS10050 (NCTC8738_02128)	htrA	1964278..1965528 (+)	1251	WP_020917669.1	S1C family serine protease	Regulator
DQM48_RS10055 (NCTC8738_02129)	spo0J	1965596..1966378 (+)	783	WP_020917670.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 416 a.a.
• Molecular weight: 43306.51 Da
• Isoelectric Point: 4.7284

>NTDB_id=1137847 DQM48_RS10050 WP_020917669.1 1964278..1965528(+) (htrA) [Streptococcus lutetiensis strain NCTC8738]
MKKITFQKVNYKKILKPLSVILVGFIGGVAGTLLILNMAGISINNVSGSSTKTTTSKVSYSNTNDTTKAVEKVREAVVSV
INYQSNSSSNDLYMQMFGGNLDNNTNNGSDSDLSIASEGSGVIYKKDGNSAYVVTNNHVVDGASQIEIMLSDGTKVVGEL
VGTDTYSDIAVVKIASDKVTTVAEFANSDKITVGETAIAIGSPLGTDYANSVTQGIVSSLSRTVTMTNDDGETISTNAIQ
TDAAINPGNSGGALINIEGQVIGINSSKISSTSDSGSGNSVEGMGFAIPANDVVKIINQLEANGKVIRPALGITMANLSD
LSTTTISRLNIPTSVTSGIVVASVQSGMPAEGVLKKYDVITAIDDKDVSSITDLQSVLYGHSTGDSIKVTFYRGTDKKTE
TIKLTKTTQDLSSSNQ

Nucleotide

• Length: 1251 bp

>NTDB_id=1137847 DQM48_RS10050 WP_020917669.1 1964278..1965528(+) (htrA) [Streptococcus lutetiensis strain NCTC8738]
GTGAAAAAAATAACATTTCAAAAAGTCAATTACAAAAAAATCCTTAAACCACTATCCGTTATTTTAGTTGGTTTCATCGG
AGGAGTTGCTGGGACCTTACTCATTTTGAATATGGCTGGCATCTCAATCAATAATGTTAGTGGTTCAAGTACAAAAACTA
CAACAAGTAAAGTAAGTTACTCAAATACTAATGATACGACAAAAGCTGTCGAAAAAGTGAGAGAAGCAGTCGTATCAGTC
ATCAATTATCAATCAAATAGCTCTTCAAATGATTTGTATATGCAAATGTTTGGTGGCAATTTAGACAATAACACTAATAA
TGGATCAGATAGTGATTTAAGTATCGCTAGTGAAGGTTCTGGGGTTATTTACAAAAAAGACGGCAATTCTGCTTATGTCG
TTACTAATAACCACGTTGTCGATGGTGCTAGTCAAATCGAAATCATGCTTTCTGACGGTACAAAAGTAGTCGGTGAATTA
GTCGGTACCGATACATACTCAGATATCGCCGTTGTCAAAATTGCTTCTGATAAAGTCACAACGGTAGCTGAATTTGCTAA
TTCAGATAAAATTACTGTTGGTGAAACAGCCATTGCTATTGGTAGCCCTCTAGGTACTGATTATGCTAACTCTGTGACAC
AAGGAATTGTCTCAAGTCTAAGCCGTACAGTTACAATGACTAACGACGATGGCGAAACAATTTCAACCAATGCTATCCAA
ACTGATGCCGCTATTAACCCAGGTAACTCTGGTGGTGCTTTGATTAACATTGAAGGACAAGTAATAGGTATTAATTCAAG
TAAAATCTCTTCTACCTCAGATTCTGGATCAGGTAATTCTGTAGAAGGTATGGGATTTGCTATTCCAGCTAATGATGTGG
TTAAAATTATTAATCAATTAGAAGCAAACGGAAAAGTTATTCGTCCAGCACTTGGTATCACAATGGCTAACCTAAGCGAT
TTATCAACAACAACAATCAGTCGCCTAAATATTCCAACTAGCGTCACATCTGGTATCGTCGTTGCTTCAGTTCAATCAGG
TATGCCTGCTGAAGGAGTACTTAAAAAATACGATGTAATCACAGCTATTGATGATAAAGATGTCTCTTCTATCACAGATC
TTCAAAGTGTTCTTTACGGTCATTCAACTGGAGATTCTATTAAAGTAACCTTCTATCGTGGTACTGACAAGAAAACAGAA
ACTATTAAACTAACGAAAACAACACAAGACCTCTCTTCATCAAATCAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (119-264)

• Peptidase family M50 (Peptidase_M50) (59-410)

• PDZ domain (PDZ_2) (309-404)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	64.838	96.394	0.625
htrA	Streptococcus gordonii str. Challis substr. CH1	60.741	97.356	0.591
htrA	Streptococcus mitis NCTC 12261	58.596	99.279	0.582
htrA	Streptococcus pneumoniae TIGR4	58.968	97.837	0.577
htrA	Streptococcus pneumoniae D39	58.968	97.837	0.577
htrA	Streptococcus pneumoniae Rx1	58.968	97.837	0.577
htrA	Streptococcus pneumoniae R6	58.968	97.837	0.577