Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   DQM48_RS05550 Genome accession   NZ_LS483348
Coordinates   1059755..1060429 (-) Length   224 a.a.
NCBI ID   WP_020916820.1    Uniprot ID   A0AB33ALR7
Organism   Streptococcus lutetiensis strain NCTC8738     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1054755..1065429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM48_RS05525 (NCTC8738_01139) - 1054928..1055521 (-) 594 WP_020916816.1 class I SAM-dependent methyltransferase -
  DQM48_RS05530 (NCTC8738_01140) coaA 1055653..1056573 (+) 921 WP_020916817.1 type I pantothenate kinase -
  DQM48_RS05535 (NCTC8738_01141) rpsT 1056649..1056900 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  DQM48_RS05540 - 1057032..1058394 (+) 1363 Protein_1028 IS3 family transposase -
  DQM48_RS05545 (NCTC8738_01146) ciaH 1058437..1059765 (-) 1329 WP_020916819.1 sensor histidine kinase Regulator
  DQM48_RS05550 (NCTC8738_01147) ciaR 1059755..1060429 (-) 675 WP_020916820.1 response regulator transcription factor Regulator
  DQM48_RS05555 (NCTC8738_01148) - 1060597..1063140 (-) 2544 WP_020916821.1 M1 family metallopeptidase -
  DQM48_RS05560 (NCTC8738_01149) phoU 1063371..1064024 (-) 654 WP_020916822.1 phosphate signaling complex protein PhoU -
  DQM48_RS05565 (NCTC8738_01150) pstB 1064055..1064813 (-) 759 WP_020916823.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25402.03 Da        Isoelectric Point: 4.3421

>NTDB_id=1137825 DQM48_RS05550 WP_020916820.1 1059755..1060429(-) (ciaR) [Streptococcus lutetiensis strain NCTC8738]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKGGFQVLKELREQGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNDNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTSFAKNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1137825 DQM48_RS05550 WP_020916820.1 1059755..1060429(-) (ciaR) [Streptococcus lutetiensis strain NCTC8738]
ATGATTAAGATTTTATTAGTAGAAGATGATTTGAGTTTATCGAATTCAATCTTTGATTTTTTAGACGATTTTGCGGATGT
TATGCAAGTCTTTGATGGTGAAGAAGGACTTTATGAGGCAGAAAGTGGTGTTTATGACCTTATTTTGCTTGATCTGATGT
TGCCAGAAAAAGGTGGTTTCCAAGTTCTGAAAGAATTACGTGAACAAGGTATTACGACACCTGTCTTAATTATGACTGCA
AAAGAAAGCCTTGATGATAAAGGACATGGCTTTGAACTTGGTGCAGATGACTATTTGACAAAACCATTTTATCTTGAAGA
ATTAAAGATGCGCATTCAAGCGCTTTTGAAACGCTCTGGAAAATTCAACGATAATACTCTTTCTTACCACGAATTAACAG
CCGATACATCAACTAACACAACAACTGTTAACGGTGAAAAGGTTGAGTTACTAGGTAAAGAATTTGATTTACTGGTTTAT
TTCTTGCAAAACCAAAATGTTATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGATTTGATAGCGATACTACAAT
TTCAGTTGTTGAAGTTTATGTTTCTAAGATTCGCAAAAAATTAAAAGGAACAAGTTTTGCTAAAAATCTACAAACACTTC
GTAGTGTAGGATATATTCTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.825

99.554

0.924
  ciaR Streptococcus pneumoniae Rx1

87.946

100

0.879
  ciaR Streptococcus pneumoniae D39

87.946

100

0.879
  ciaR Streptococcus pneumoniae R6

87.946

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.885

100

0.384
  vicR Streptococcus mutans UA159

34.764

100

0.362

Multiple sequence alignment