Detailed information NTG1137793

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQM48_RS00355
• Genome accession: NZ_LS483348
• Coordinates: 51370..52248 (+)
• Length: 292 a.a.
• NCBI ID: WP_172454540.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC8738
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 46370..57248

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM48_RS00325 (NCTC8738_00065)	purD	46428..47690 (+)	1263	WP_111698141.1	phosphoribosylamine--glycine ligase	-
DQM48_RS00330 (NCTC8738_00066)	-	47680..48129 (+)	450	WP_111698143.1	DUF523 domain-containing protein	-
DQM48_RS00335 (NCTC8738_00067)	purE	48129..48617 (+)	489	WP_058813548.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQM48_RS00340 (NCTC8738_00068)	purK	48604..49695 (+)	1092	WP_111698145.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQM48_RS10265	-	49698..49793 (+)	96	Protein_34	phosphoribosylaminoimidazole carboxylase	-
DQM48_RS00350 (NCTC8738_00069)	purB	49883..51181 (+)	1299	WP_058813549.1	adenylosuccinate lyase	-
DQM48_RS00355 (NCTC8738_00070)	comR	51370..52248 (+)	879	WP_172454540.1	helix-turn-helix domain-containing protein	Regulator
DQM48_RS00360 (NCTC8738_00071)	ruvB	52450..53448 (+)	999	WP_111698149.1	Holliday junction branch migration DNA helicase RuvB	-
DQM48_RS10215 (NCTC8738_00072)	-	53621..53821 (+)	201	WP_197708497.1	DUF7010 family protein	-
DQM48_RS10710 (NCTC8738_00073)	-	53788..54153 (+)	366	WP_231853261.1	DUF7010 family protein	-
DQM48_RS00370 (NCTC8738_00074)	-	54392..54823 (+)	432	WP_014334179.1	low molecular weight protein-tyrosine-phosphatase	-
DQM48_RS00375 (NCTC8738_00075)	-	54841..55221 (+)	381	WP_006531314.1	membrane protein	-
DQM48_RS00380 (NCTC8738_00076)	-	55218..57011 (+)	1794	WP_020916207.1	acyltransferase family protein	-

Sequence

Protein

• Length: 292 a.a.
• Molecular weight: 34470.29 Da
• Isoelectric Point: 4.5999

>NTDB_id=1137793 DQM48_RS00355 WP_172454540.1 51370..52248(+) (comR) [Streptococcus lutetiensis strain NCTC8738]
MREEKEISREEFCGDETELSVRQLARIELNQSIPNLSKASFIANRLGVKLGTLTDGDSLELPKRYKELKYLLLRTPTYGD
QVRLDRKNDYFDEIAEVFYDVIPEEERLIIDCLQSKFDVHFSEDVNFGEGILNDYFGQVNRKKVFTINDLILIDLYFACL
SSAKKFEGIYSLDFYDDLMKRLVNQKHVSPETDLILNNVLLNNIDLAFQFKREYYIERVITISEKIMTEIHDFQRRPILS
LVEWKYYLKFKHDFALAEQSFTNATLFARLVGDTYLENKLKEEWQLDIDAVE

Nucleotide

• Length: 879 bp

>NTDB_id=1137793 DQM48_RS00355 WP_172454540.1 51370..52248(+) (comR) [Streptococcus lutetiensis strain NCTC8738]
ATGCGGGAGGAAAAGGAAATATCACGTGAAGAATTCTGTGGGGATGAAACAGAATTATCGGTAAGACAATTAGCCAGAAT
TGAGTTGAACCAATCAATACCCAATCTCAGTAAAGCAAGCTTTATTGCCAATCGTCTGGGAGTGAAATTAGGTACCTTAA
CTGATGGTGACAGTTTAGAATTACCTAAGCGGTATAAAGAGTTGAAGTATTTACTTCTTCGAACACCTACATATGGAGAC
CAGGTACGACTTGATCGAAAAAATGACTATTTTGATGAGATTGCTGAAGTATTTTATGATGTTATTCCAGAAGAAGAACG
GTTAATCATTGATTGTTTACAATCAAAATTCGATGTTCATTTTAGTGAAGATGTCAATTTTGGAGAGGGTATTTTAAATG
ATTATTTTGGTCAAGTTAATCGAAAGAAAGTTTTTACCATTAATGATTTAATTTTGATTGATCTTTACTTTGCTTGTCTT
TCTTCTGCTAAGAAGTTTGAAGGAATTTATAGTTTGGATTTTTACGATGATTTGATGAAAAGATTGGTAAATCAAAAGCA
TGTTTCACCTGAGACTGATTTAATTTTAAATAATGTATTGTTAAATAATATTGACTTAGCATTCCAATTTAAACGAGAAT
ATTATATTGAGCGTGTTATTACAATCAGTGAAAAAATTATGACAGAGATTCATGATTTTCAACGTCGTCCGATTTTAAGT
TTGGTGGAGTGGAAGTATTATCTGAAATTTAAACATGACTTTGCTTTAGCAGAACAGTCATTTACGAATGCAACATTATT
TGCACGATTGGTTGGTGATACTTATTTAGAGAATAAACTTAAAGAAGAATGGCAACTTGATATTGATGCTGTGGAGTAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (62-284)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	99.658	100	0.997
comR	Streptococcus mutans UA159	53.125	98.63	0.524
comR	Streptococcus pyogenes MGAS8232	51.37	100	0.514
comR	Streptococcus pyogenes MGAS315	45.89	100	0.459
comR	Streptococcus suis D9	36.86	100	0.37
comR	Streptococcus suis P1/7	37.153	98.63	0.366
comR	Streptococcus suis 05ZYH33	37.153	98.63	0.366