Detailed information NTG1137772

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM50_RS05525
• Genome accession: NZ_LS483347
• Coordinates: 1026112..1026948 (-)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8324
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1021112..1031948

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM50_RS05500 (NCTC8324_01114)	-	1021344..1022336 (-)	993	WP_023610823.1	D-lactate dehydrogenase	-
DQM50_RS05505 (NCTC8324_01115)	-	1022351..1022904 (-)	554	Protein_1011	PTS sugar transporter subunit IIC	-
DQM50_RS09970	-	1022917..1023801 (+)	885	Protein_1012	LysR family transcriptional regulator	-
DQM50_RS05520 (NCTC8324_01117)	topA	1023876..1026005 (-)	2130	WP_085613843.1	type I DNA topoisomerase	-
DQM50_RS05525 (NCTC8324_01118)	dprA	1026112..1026948 (-)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
DQM50_RS05530 (NCTC8324_01119)	-	1027013..1027804 (-)	792	WP_023610685.1	ribonuclease HII	-
DQM50_RS05535 (NCTC8324_01120)	ylqF	1027794..1028642 (-)	849	WP_085613844.1	ribosome biogenesis GTPase YlqF	-
DQM50_RS05540 (NCTC8324_01121)	-	1028861..1029301 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQM50_RS05545 (NCTC8324_01122)	trhA	1029298..1029948 (+)	651	WP_023079408.1	PAQR family membrane homeostasis protein TrhA	-
DQM50_RS05550 (NCTC8324_01123)	-	1030065..1030976 (+)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
DQM50_RS05555 (NCTC8324_01124)	-	1031026..1031397 (-)	372	WP_111688479.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=1137772 DQM50_RS05525 WP_023079425.1 1026112..1026948(-) (dprA) [Streptococcus pyogenes strain NCTC8324]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1137772 DQM50_RS05525 WP_023079425.1 1026112..1026948(-) (dprA) [Streptococcus pyogenes strain NCTC8324]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367