Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   DQM73_RS05970 Genome accession   NZ_LS483346
Coordinates   1222926..1223768 (-) Length   280 a.a.
NCBI ID   WP_002917211.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11085     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1217926..1228768
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS05950 (NCTC11085_01162) trmFO 1218029..1219363 (-) 1335 WP_032908168.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  DQM73_RS12420 (NCTC11085_01163) - 1219772..1220191 (-) 420 WP_002924664.1 hypothetical protein -
  DQM73_RS05960 (NCTC11085_01164) - 1220188..1220688 (-) 501 WP_002924662.1 hypothetical protein -
  DQM73_RS05965 (NCTC11085_01165) topA 1220748..1222841 (-) 2094 WP_002924660.1 type I DNA topoisomerase -
  DQM73_RS05970 (NCTC11085_01166) dprA/cilB/dalA 1222926..1223768 (-) 843 WP_002917211.1 DNA-processing protein DprA Machinery gene
  DQM73_RS05975 (NCTC11085_01167) - 1223900..1224463 (-) 564 WP_002917210.1 sugar O-acetyltransferase -
  DQM73_RS05980 (NCTC11085_01168) - 1224439..1225281 (-) 843 WP_002924658.1 PRD domain-containing protein -
  DQM73_RS05985 (NCTC11085_01169) - 1225299..1226063 (-) 765 WP_002924656.1 ribonuclease HII -
  DQM73_RS05990 (NCTC11085_01170) ylqF 1226050..1226901 (-) 852 WP_002924654.1 ribosome biogenesis GTPase YlqF -
  DQM73_RS05995 (NCTC11085_01171) - 1227043..1227381 (-) 339 WP_002895476.1 ATP cone domain-containing protein -
  DQM73_RS06005 (NCTC11085_01172) dapA 1227621..1228556 (-) 936 WP_002924651.1 4-hydroxy-tetrahydrodipicolinate synthase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30936.58 Da        Isoelectric Point: 6.4912

>NTDB_id=1137705 DQM73_RS05970 WP_002917211.1 1222926..1223768(-) (dprA/cilB/dalA) [Streptococcus sanguinis strain NCTC11085]
MNNFEIYKMKKAGLTNHQVLNVLRYAESKDGNLSLRDKAVVSECRNPALFIEKYKRLDLPALKEEFELFPSFSILDDIYP
WDLCEIYDAPTLLFYQGNLNLLELPKAAVVGSRDSSKQGNASVQKIIKELNNELVIVSGLARGIDTAAHMAALQNGGQTI
AVIGTGLDVFYPKANKKLQAYIGKNHLLLTEYGPGEQPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGKSDGCHHLIQEGAKCITSGSDVLSEFDF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=1137705 DQM73_RS05970 WP_002917211.1 1222926..1223768(-) (dprA/cilB/dalA) [Streptococcus sanguinis strain NCTC11085]
ATGAATAATTTTGAGATTTATAAAATGAAAAAAGCTGGCTTGACTAATCATCAGGTTTTAAATGTTTTGAGATACGCCGA
GAGTAAAGATGGCAATCTTTCTCTGCGAGATAAGGCTGTCGTATCTGAGTGCCGCAATCCTGCTCTCTTTATTGAGAAAT
ACAAGAGGCTTGATTTACCGGCTTTGAAAGAAGAATTTGAACTTTTTCCGTCCTTTTCTATCTTGGATGATATTTATCCT
TGGGATTTATGCGAAATTTACGATGCCCCGACCTTGCTATTTTATCAGGGAAATCTAAATCTACTAGAATTGCCCAAGGC
TGCAGTCGTTGGCAGTCGAGACAGCAGTAAGCAAGGAAATGCCTCTGTACAAAAGATTATCAAAGAGCTAAACAATGAAT
TGGTTATCGTCAGTGGCCTGGCTCGAGGGATTGATACAGCGGCTCATATGGCTGCCCTGCAAAACGGAGGTCAGACCATT
GCTGTCATTGGTACTGGATTAGACGTCTTTTATCCCAAGGCCAACAAAAAATTACAAGCTTACATTGGCAAAAATCATTT
ATTGCTGACAGAGTATGGTCCAGGTGAACAGCCCTTGAAATTTCATTTTCCAGAGCGGAATCGTATCATCGCTGGTCTAT
GCCGAGGCGTCATCGTGGCGGAAGCCAAGATGCGCTCAGGCAGTCTGATTACCTGTGAGCGAGCCATGGAAGAAGGGCGA
GATGTCTTTGCTATTCCAGGGTCTATTTTAGATGGAAAATCTGACGGTTGCCATCATTTGATTCAAGAGGGTGCAAAGTG
CATCACATCAGGCTCTGACGTTCTTTCTGAGTTTGATTTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(74-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

77.143

100

0.771
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.786

100

0.768
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.786

100

0.768
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.786

100

0.768
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.786

100

0.768
  dprA/cilB/dalA Streptococcus mitis SK321

76.429

100

0.764
  dprA Streptococcus mutans UA159

67.143

100

0.671
  dprA Lactococcus lactis subsp. cremoris KW2

56.835

99.286

0.564
  dprA Legionella pneumophila strain ERS1305867

40.345

100

0.418

Multiple sequence alignment