Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DQL23_RS09035 Genome accession   NZ_LS483341
Coordinates   1868784..1869485 (-) Length   233 a.a.
NCBI ID   WP_008809004.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7865     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1863784..1874485
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS09015 (NCTC7865_01819) rnc 1865302..1866000 (-) 699 WP_045502139.1 ribonuclease III -
  DQL23_RS09020 (NCTC7865_01820) - 1866243..1866599 (-) 357 WP_060553990.1 YbaN family protein -
  DQL23_RS09025 (NCTC7865_01821) vicX 1866634..1867437 (-) 804 WP_060553991.1 MBL fold metallo-hydrolase Regulator
  DQL23_RS09030 (NCTC7865_01822) micB 1867430..1868791 (-) 1362 WP_053794800.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL23_RS09035 (NCTC7865_01823) micA 1868784..1869485 (-) 702 WP_008809004.1 response regulator YycF Regulator
  DQL23_RS09040 (NCTC7865_01824) thrS 1869695..1871638 (-) 1944 WP_060553992.1 threonine--tRNA ligase -
  DQL23_RS09045 (NCTC7865_01825) - 1871649..1872275 (-) 627 WP_196755809.1 AAA family ATPase -
  DQL23_RS09050 (NCTC7865_01827) - 1872543..1872908 (-) 366 WP_060553993.1 hypothetical protein -
  DQL23_RS09055 (NCTC7865_01828) - 1872944..1874257 (-) 1314 WP_060553994.1 glycosyltransferase family 4 protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26790.54 Da        Isoelectric Point: 4.6297

>NTDB_id=1137500 DQL23_RS09035 WP_008809004.1 1868784..1869485(-) (micA) [Streptococcus gordonii strain NCTC7865]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAENPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRSEFAVDTQESEKGSNELTVGELQILPDAFVAKKHGEELELTH
REFELLYHLASHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1137500 DQL23_RS09035 WP_008809004.1 1868784..1869485(-) (micA) [Streptococcus gordonii strain NCTC7865]
ATGAAGAAAATATTAGTTGTAGATGATGAAAAACCAATTTCAGATATTATAAAATTTAATATGGTAAAAGAGGGCTATGA
AGTTGTTACGGCTTTTGATGGCCGTGAAGCTCTTGAGATGTTTGAAGCAGAAAATCCTGATATTTTGATTTTGGATTTGA
TGTTGCCAGAATTGGACGGGCTAGAAGTAGCACGCACCATTCGGAAGACCAGTAATGTTCCAATTATTGTCCTATCGGCC
AAAGATAGTGAGTTTGATAAAGTTATCGGCCTCGAAATTGGAGCAGACGACTATGTGACCAAGCCTTTCTCTAACCGTGA
GCTCCAAGCTCGTGTCAAGGCTATTTTGCGACGTTCAGAATTTGCTGTAGATACCCAAGAAAGTGAAAAGGGCTCGAATG
AGTTGACAGTGGGCGAATTGCAAATTTTACCAGATGCTTTTGTTGCTAAGAAACATGGCGAGGAACTAGAATTAACCCAT
CGTGAGTTTGAATTACTCTACCATTTGGCCAGTCATGTTGGTCAAGTCATGACACGCGAACACCTGTTAGAGACAGTTTG
GGGTTATGATTATTTTGGTGATGTACGCACTGTTGATGTGACGATTCGCCGCCTACGTGAAAAGATTGAAGATACGCCAA
GCCGACCAGAGTATATTTTAACTCGTCGTGGCGTTGGCTACTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.12

100

0.841
  vicR Streptococcus mutans UA159

79.574

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.5

99.571

0.373

Multiple sequence alignment