Detailed information NTG1137254

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL03_RS04750
• Genome accession: NZ_LS483337
• Coordinates: 911859..912695 (+)
• Length: 278 a.a.
• NCBI ID: WP_020905195.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12047
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 906859..917695

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL03_RS04720 (NCTC12047_00933)	-	907413..907781 (+)	369	WP_010922310.1	hypothetical protein	-
DQL03_RS04725 (NCTC12047_00934)	-	907831..908742 (-)	912	WP_020905190.1	diacylglycerol/lipid kinase family protein	-
DQL03_RS04730 (NCTC12047_00935)	trhA	908859..909509 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL03_RS04735 (NCTC12047_00936)	-	909506..909946 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQL03_RS04740 (NCTC12047_00937)	ylqF	910165..911013 (+)	849	WP_020905193.1	ribosome biogenesis GTPase YlqF	-
DQL03_RS04745 (NCTC12047_00938)	-	911003..911794 (+)	792	WP_032464377.1	ribonuclease HII	-
DQL03_RS04750 (NCTC12047_00939)	dprA	911859..912695 (+)	837	WP_020905195.1	DNA-processing protein DprA	Machinery gene
DQL03_RS04755 (NCTC12047_00940)	topA	912802..914931 (+)	2130	WP_032464379.1	type I DNA topoisomerase	-
DQL03_RS04760 (NCTC12047_00941)	trmFO	915066..916412 (+)	1347	WP_111674926.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.00 Da
• Isoelectric Point: 9.2514

>NTDB_id=1137254 DQL03_RS04750 WP_020905195.1 911859..912695(+) (dprA) [Streptococcus pyogenes strain NCTC12047]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1137254 DQL03_RS04750 WP_020905195.1 911859..912695(+) (dprA) [Streptococcus pyogenes strain NCTC12047]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367