Detailed information NTG1137195

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL08_RS04520
• Genome accession: NZ_LS483336
• Coordinates: 880080..880916 (+)
• Length: 278 a.a.
• NCBI ID: WP_023611073.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12046
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 875080..885916

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL08_RS04490 (NCTC12046_00889)	-	875628..876002 (+)	375	WP_023611058.1	hypothetical protein	-
DQL08_RS04495 (NCTC12046_00890)	-	876052..876963 (-)	912	WP_023611071.1	diacylglycerol/lipid kinase family protein	-
DQL08_RS04500 (NCTC12046_00891)	trhA	877080..877730 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL08_RS04505 (NCTC12046_00892)	-	877727..878167 (-)	441	WP_023611062.1	DUF1836 domain-containing protein	-
DQL08_RS04510 (NCTC12046_00893)	ylqF	878386..879234 (+)	849	WP_023611048.1	ribosome biogenesis GTPase YlqF	-
DQL08_RS04515 (NCTC12046_00894)	-	879224..880015 (+)	792	WP_023611055.1	ribonuclease HII	-
DQL08_RS04520 (NCTC12046_00895)	dprA	880080..880916 (+)	837	WP_023611073.1	DNA-processing protein DprA	Machinery gene
DQL08_RS04525 (NCTC12046_00896)	topA	881024..883153 (+)	2130	WP_023611066.1	type I DNA topoisomerase	-
DQL08_RS09690 (NCTC12046_00897)	-	883228..883969 (-)	742	Protein_818	LysR family transcriptional regulator	-
DQL08_RS04540 (NCTC12046_00898)	-	884009..884554 (+)	546	Protein_819	PTS sugar transporter subunit IIC	-
DQL08_RS04545 (NCTC12046_00899)	-	884569..885561 (+)	993	WP_023611458.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31018.97 Da
• Isoelectric Point: 8.8230

>NTDB_id=1137195 DQL08_RS04520 WP_023611073.1 880080..880916(+) (dprA) [Streptococcus pyogenes strain NCTC12046]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEESR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1137195 DQL08_RS04520 WP_023611073.1 880080..880916(+) (dprA) [Streptococcus pyogenes strain NCTC12046]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAAGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367