Detailed information NTG1137137

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL44_RS04700
• Genome accession: NZ_LS483335
• Coordinates: 896248..897084 (+)
• Length: 278 a.a.
• NCBI ID: WP_111677257.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8332
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 891248..902084

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL44_RS04670 (NCTC8332_00923)	-	891806..892174 (+)	369	WP_010922310.1	hypothetical protein	-
DQL44_RS04675 (NCTC8332_00924)	-	892224..893135 (-)	912	WP_111677253.1	diacylglycerol/lipid kinase family protein	-
DQL44_RS04680 (NCTC8332_00925)	trhA	893252..893902 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL44_RS04685 (NCTC8332_00926)	-	893907..894335 (-)	429	WP_111677254.1	DUF1836 domain-containing protein	-
DQL44_RS04690 (NCTC8332_00927)	ylqF	894554..895402 (+)	849	WP_111677255.1	ribosome biogenesis GTPase YlqF	-
DQL44_RS04695 (NCTC8332_00928)	-	895392..896183 (+)	792	WP_111677256.1	ribonuclease HII	-
DQL44_RS04700 (NCTC8332_00929)	dprA	896248..897084 (+)	837	WP_111677257.1	DNA-processing protein DprA	Machinery gene
DQL44_RS04705 (NCTC8332_00930)	topA	897191..899320 (+)	2130	WP_111677258.1	type I DNA topoisomerase	-
DQL44_RS10115	-	899397..900281 (-)	885	Protein_863	LysR family transcriptional regulator	-
DQL44_RS04720 (NCTC8332_00932)	-	900294..900860 (+)	567	Protein_864	PTS sugar transporter subunit IIC	-
DQL44_RS04725 (NCTC8332_00933)	-	900875..901867 (+)	993	WP_111677261.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30897.92 Da
• Isoelectric Point: 9.2512

>NTDB_id=1137137 DQL44_RS04700 WP_111677257.1 896248..897084(+) (dprA) [Streptococcus pyogenes strain NCTC8332]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRLSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEGGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDIFSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1137137 DQL44_RS04700 WP_111677257.1 896248..897084(+) (dprA) [Streptococcus pyogenes strain NCTC8332]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACTCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGAAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAGAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGGAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCTTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.547	100	0.665
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363