Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQL44_RS02345 Genome accession   NZ_LS483335
Coordinates   428384..429094 (+) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8332     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 423384..434094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL44_RS02320 (NCTC8332_00453) - 423395..424108 (+) 714 WP_301182272.1 MIP/aquaporin family protein -
  DQL44_RS02325 (NCTC8332_00454) - 424242..424811 (+) 570 WP_111677104.1 hypothetical protein -
  DQL44_RS02330 (NCTC8332_00455) - 424780..425928 (+) 1149 WP_111677105.1 acetyl-CoA C-acyltransferase -
  DQL44_RS02335 (NCTC8332_00456) - 425885..427132 (+) 1248 WP_111677106.1 AMP-binding protein -
  DQL44_RS02340 (NCTC8332_00457) - 427188..428222 (+) 1035 WP_172448831.1 DUF3114 domain-containing protein -
  DQL44_RS02345 (NCTC8332_00458) vicR 428384..429094 (+) 711 WP_002985645.1 response regulator YycF Regulator
  DQL44_RS02350 (NCTC8332_00459) vicK 429087..430439 (+) 1353 WP_111677108.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL44_RS02355 (NCTC8332_00460) vicX 430443..431252 (+) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  DQL44_RS02360 (NCTC8332_00461) rnc 431683..432375 (+) 693 WP_002985639.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=1137130 DQL44_RS02345 WP_002985645.1 428384..429094(+) (vicR) [Streptococcus pyogenes strain NCTC8332]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1137130 DQL44_RS02345 WP_002985645.1 428384..429094(+) (vicR) [Streptococcus pyogenes strain NCTC8332]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCGCGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAGACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGTGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ATACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364

Multiple sequence alignment