Detailed information NTG1137032

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL30_RS04795
• Genome accession: NZ_LS483333
• Coordinates: 914407..915243 (-)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12048
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 909407..920243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL30_RS04770 (NCTC12048_00951)	-	909625..910617 (-)	993	WP_009880715.1	D-lactate dehydrogenase	-
DQL30_RS04775 (NCTC12048_00952)	-	910632..911198 (-)	567	Protein_868	PTS sugar transporter subunit IIC	-
DQL30_RS09135	-	911238..912095 (+)	858	Protein_869	LysR family transcriptional regulator	-
DQL30_RS04790 (NCTC12048_00954)	topA	912170..914299 (-)	2130	WP_111713773.1	type I DNA topoisomerase	-
DQL30_RS04795 (NCTC12048_00955)	dprA	914407..915243 (-)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
DQL30_RS04800 (NCTC12048_00956)	-	915308..916099 (-)	792	WP_109991958.1	ribonuclease HII	-
DQL30_RS04805 (NCTC12048_00957)	ylqF	916089..916937 (-)	849	WP_111713774.1	ribosome biogenesis GTPase YlqF	-
DQL30_RS04810 (NCTC12048_00958)	-	917156..917596 (+)	441	WP_111713775.1	DUF1836 domain-containing protein	-
DQL30_RS04815 (NCTC12048_00959)	trhA	917593..918243 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL30_RS04820 (NCTC12048_00960)	-	918360..919271 (+)	912	WP_047235287.1	diacylglycerol/lipid kinase family protein	-
DQL30_RS04825 (NCTC12048_00961)	-	919321..919689 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=1137032 DQL30_RS04795 WP_023079425.1 914407..915243(-) (dprA) [Streptococcus pyogenes strain NCTC12048]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1137032 DQL30_RS04795 WP_023079425.1 914407..915243(-) (dprA) [Streptococcus pyogenes strain NCTC12048]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367