Detailed information NTG1136862

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL25_RS05060
• Genome accession: NZ_LS483330
• Coordinates: 964708..965544 (-)
• Length: 278 a.a.
• NCBI ID: WP_111703285.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8328
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 959708..970544

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL25_RS05050 (NCTC8328_01012)	trmFO	960990..962336 (-)	1347	WP_111703283.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
DQL25_RS05055 (NCTC8328_01013)	topA	962471..964600 (-)	2130	WP_111703284.1	type I DNA topoisomerase	-
DQL25_RS05060 (NCTC8328_01014)	dprA	964708..965544 (-)	837	WP_111703285.1	DNA-processing protein DprA	Machinery gene
DQL25_RS05065 (NCTC8328_01015)	-	965609..966400 (-)	792	WP_111703286.1	ribonuclease HII	-
DQL25_RS05070 (NCTC8328_01016)	ylqF	966390..967238 (-)	849	WP_111703287.1	ribosome biogenesis GTPase YlqF	-
DQL25_RS05075 (NCTC8328_01017)	-	967457..967897 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQL25_RS05080 (NCTC8328_01018)	trhA	967894..968544 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL25_RS05085 (NCTC8328_01019)	-	968661..969572 (+)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
DQL25_RS05090 (NCTC8328_01020)	-	969622..970059 (-)	438	WP_111703288.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30915.94 Da
• Isoelectric Point: 9.4250

>NTDB_id=1136862 DQL25_RS05060 WP_111703285.1 964708..965544(-) (dprA) [Streptococcus pyogenes strain NCTC8328]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEGALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1136862 DQL25_RS05060 WP_111703285.1 964708..965544(-) (dprA) [Streptococcus pyogenes strain NCTC8328]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAACAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGGAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367