Detailed information NTG1136803

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL27_RS03885
• Genome accession: NZ_LS483329
• Coordinates: 739940..740776 (-)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12058
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 734940..745776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL27_RS03860 (NCTC12058_00772)	-	735180..736172 (-)	993	WP_031488271.1	D-lactate dehydrogenase	-
DQL27_RS03865 (NCTC12058_00773)	-	736187..736732 (-)	546	Protein_704	PTS sugar transporter subunit IIC	-
DQL27_RS09020	-	736772..737629 (+)	858	Protein_705	LysR family transcriptional regulator	-
DQL27_RS03880 (NCTC12058_00775)	topA	737704..739833 (-)	2130	WP_011017773.1	type I DNA topoisomerase	-
DQL27_RS03885 (NCTC12058_00776)	dprA	739940..740776 (-)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
DQL27_RS03890 (NCTC12058_00777)	-	740841..741632 (-)	792	WP_031488275.1	ribonuclease HII	-
DQL27_RS03895 (NCTC12058_00778)	ylqF	741622..742470 (-)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
DQL27_RS03900 (NCTC12058_00779)	-	742689..743129 (+)	441	WP_031488277.1	DUF1836 domain-containing protein	-
DQL27_RS03905 (NCTC12058_00780)	trhA	743126..743776 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL27_RS03910 (NCTC12058_00781)	-	743893..744804 (+)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
DQL27_RS03915 (NCTC12058_00782)	-	744854..745291 (-)	438	WP_031488279.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=1136803 DQL27_RS03885 WP_031488274.1 739940..740776(-) (dprA) [Streptococcus pyogenes strain NCTC12058]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1136803 DQL27_RS03885 WP_031488274.1 739940..740776(-) (dprA) [Streptococcus pyogenes strain NCTC12058]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363