Detailed information NTG1136715

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQL47_RS00280
• Genome accession: NZ_LS483328
• Coordinates: 47687..48601 (+)
• Length: 304 a.a.
• NCBI ID: WP_042669756.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC12090
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42687..53601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL47_RS00260 (NCTC12090_00052)	purE	43850..44338 (+)	489	WP_021320238.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQL47_RS00265 (NCTC12090_00053)	purK	44325..45416 (+)	1092	WP_111689735.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQL47_RS00270 (NCTC12090_00054)	-	45426..45650 (+)	225	WP_037582407.1	hypothetical protein	-
DQL47_RS10520	-	45675..45779 (+)	105	WP_370444775.1	hypothetical protein	-
DQL47_RS00275 (NCTC12090_00055)	purB	46096..47388 (+)	1293	WP_038674659.1	adenylosuccinate lyase	-
DQL47_RS00280 (NCTC12090_00056)	comR	47687..48601 (+)	915	WP_042669756.1	helix-turn-helix domain-containing protein	Regulator
DQL47_RS10535 (NCTC12090_00057)	comS	48684..48782 (+)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
DQL47_RS00285 (NCTC12090_00058)	ruvB	48816..49817 (+)	1002	WP_042669757.1	Holliday junction branch migration DNA helicase RuvB	-
DQL47_RS00290 (NCTC12090_00059)	-	50103..50561 (+)	459	WP_012514717.1	low molecular weight protein-tyrosine-phosphatase	-
DQL47_RS00295 (NCTC12090_00060)	-	50567..50968 (+)	402	WP_111689736.1	hypothetical protein	-
DQL47_RS00300 (NCTC12090_00061)	-	50965..52746 (+)	1782	WP_111689737.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35806.34 Da
• Isoelectric Point: 4.5517

>NTDB_id=1136715 DQL47_RS00280 WP_042669756.1 47687..48601(+) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=1136715 DQL47_RS00280 WP_042669756.1 47687..48601(+) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTCGACATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTGTTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GAATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.498	98.355	0.487
comR	Streptococcus suis D9	37.874	99.013	0.375
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis P1/7	38.644	97.039	0.375