Detailed information NTG1136619

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL59_RS03460
• Genome accession: NZ_LS483326
• Coordinates: 661697..662533 (+)
• Length: 278 a.a.
• NCBI ID: WP_020905195.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12045
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 656697..667533

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL59_RS03430 (NCTC12045_00676)	-	657185..657619 (+)	435	WP_023079442.1	hypothetical protein	-
DQL59_RS03435 (NCTC12045_00677)	-	657669..658580 (-)	912	WP_023079407.1	diacylglycerol/lipid kinase family protein	-
DQL59_RS03440 (NCTC12045_00678)	trhA	658697..659347 (-)	651	WP_023079408.1	PAQR family membrane homeostasis protein TrhA	-
DQL59_RS03445 (NCTC12045_00679)	-	659344..659784 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQL59_RS03450 (NCTC12045_00680)	ylqF	660003..660851 (+)	849	WP_011184517.1	ribosome biogenesis GTPase YlqF	-
DQL59_RS03455 (NCTC12045_00681)	-	660841..661632 (+)	792	WP_111681113.1	ribonuclease HII	-
DQL59_RS03460 (NCTC12045_00682)	dprA	661697..662533 (+)	837	WP_020905195.1	DNA-processing protein DprA	Machinery gene
DQL59_RS03465 (NCTC12045_00683)	topA	662639..664768 (+)	2130	WP_111681114.1	type I DNA topoisomerase	-
DQL59_RS03470 (NCTC12045_00684)	trmFO	664903..666249 (+)	1347	WP_111681115.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.00 Da
• Isoelectric Point: 9.2514

>NTDB_id=1136619 DQL59_RS03460 WP_020905195.1 661697..662533(+) (dprA) [Streptococcus pyogenes strain NCTC12045]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1136619 DQL59_RS03460 WP_020905195.1 661697..662533(+) (dprA) [Streptococcus pyogenes strain NCTC12045]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTTGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367