Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQL35_RS08255 Genome accession   NZ_LS483325
Coordinates   1719976..1722132 (+) Length   718 a.a.
NCBI ID   WP_111678343.1    Uniprot ID   A0AAJ1PLU2
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC7022     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1714976..1727132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL35_RS10950 - 1715460..1715585 (-) 126 WP_255313937.1 hypothetical protein -
  DQL35_RS08215 - 1716108..1716293 (+) 186 WP_255313988.1 helix-turn-helix domain-containing protein -
  DQL35_RS08220 (NCTC7022_01668) - 1716395..1716976 (-) 582 WP_043031274.1 GNAT family N-acetyltransferase -
  DQL35_RS08225 (NCTC7022_01669) - 1717227..1717628 (-) 402 WP_230923698.1 bacteriocin immunity protein -
  DQL35_RS08230 (NCTC7022_01670) - 1717923..1718219 (-) 297 WP_111678339.1 bacteriocin immunity protein -
  DQL35_RS08235 - 1718219..1718407 (-) 189 WP_229297300.1 leucocin A/sakacin P family class II bacteriocin -
  DQL35_RS08245 (NCTC7022_01671) - 1719166..1719462 (-) 297 WP_111678854.1 bacteriocin immunity protein -
  DQL35_RS08250 (NCTC7022_01672) - 1719469..1719717 (-) 249 WP_111678341.1 garvicin Q family class II bacteriocin -
  DQL35_RS08255 (NCTC7022_01673) comA/nlmT 1719976..1722132 (+) 2157 WP_111678343.1 peptide cleavage/export ABC transporter Regulator
  DQL35_RS08260 (NCTC7022_01674) - 1722143..1723501 (+) 1359 WP_111678345.1 bacteriocin secretion accessory protein -
  DQL35_RS08265 (NCTC7022_01675) - 1723601..1723735 (+) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQL35_RS10980 (NCTC7022_01676) - 1723854..1725188 (-) 1335 WP_111678347.1 sensor histidine kinase -
  DQL35_RS08275 (NCTC7022_01677) comE/blpR 1725188..1725937 (-) 750 WP_111678349.1 LytR/AlgR family response regulator transcription factor Regulator
  DQL35_RS08280 (NCTC7022_01678) - 1726569..1726772 (-) 204 WP_111678351.1 TmhB bacteriocin enhancer peptide -
  DQL35_RS08285 (NCTC7022_01679) - 1726789..1727046 (-) 258 WP_111678353.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80585.75 Da        Isoelectric Point: 7.7847

>NTDB_id=1136583 DQL35_RS08255 WP_111678343.1 1719976..1722132(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVMAAKEIGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
IIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYVFNGSILENLTLGAKQGISQEDILKACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=1136583 DQL35_RS08255 WP_111678343.1 1719976..1722132(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCTTCGATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATAGGGTTTGAAACCAGACCCATTCAAGCGGATATGACCCTCTTTGACATGGCAGAT
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGTCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCA
CTTATTTTTAAACAGCGAGCCCTTATTTTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTGCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAACTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCTCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGTTATCTCTGATTTCTATCCCAGTATATACC
ATTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTCGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATCGGGCAGTTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAACAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTACAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAGCCTTATAAGGGACGTATAACCATCAACCAAAATGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATGTCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAGGGCAT
CAGCCAGGAAGACATTCTTAAAGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTGGTTCTTAATCAAG
GGCAAATCATTGAAACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-439)

Peptidase C39 family (Peptidase_C39)

(8-143)

ABC transporter (ABC_tran)

(501-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.99

99.861

0.709
  comA Streptococcus mitis SK321

67.882

99.304

0.674
  comA Streptococcus mitis NCTC 12261

67.602

99.304

0.671
  comA Streptococcus pneumoniae D39

67.181

99.304

0.667
  comA Streptococcus pneumoniae Rx1

67.181

99.304

0.667
  comA Streptococcus pneumoniae R6

67.181

99.304

0.667
  comA Streptococcus pneumoniae TIGR4

66.9

99.304

0.664
  comA Streptococcus gordonii str. Challis substr. CH1

65.358

99.304

0.649

Multiple sequence alignment