Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DQL35_RS08275 Genome accession   NZ_LS483325
Coordinates   1725188..1725937 (-) Length   249 a.a.
NCBI ID   WP_111678349.1    Uniprot ID   A0AAJ1UTB0
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC7022     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1720188..1730937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL35_RS08260 (NCTC7022_01674) - 1722143..1723501 (+) 1359 WP_111678345.1 bacteriocin secretion accessory protein -
  DQL35_RS08265 (NCTC7022_01675) - 1723601..1723735 (+) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DQL35_RS10980 (NCTC7022_01676) - 1723854..1725188 (-) 1335 WP_111678347.1 sensor histidine kinase -
  DQL35_RS08275 (NCTC7022_01677) comE/blpR 1725188..1725937 (-) 750 WP_111678349.1 LytR/AlgR family response regulator transcription factor Regulator
  DQL35_RS08280 (NCTC7022_01678) - 1726569..1726772 (-) 204 WP_111678351.1 TmhB bacteriocin enhancer peptide -
  DQL35_RS08285 (NCTC7022_01679) - 1726789..1727046 (-) 258 WP_111678353.1 Blp family class II bacteriocin -
  DQL35_RS08290 (NCTC7022_01680) - 1727522..1727782 (-) 261 WP_111678355.1 hypothetical protein -
  DQL35_RS08295 (NCTC7022_01681) - 1727819..1729144 (-) 1326 WP_111678855.1 6-phospho-alpha-glucosidase -
  DQL35_RS08300 (NCTC7022_01682) - 1729164..1730714 (-) 1551 WP_111678357.1 PTS transporter subunit EIIC -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29228.72 Da        Isoelectric Point: 8.1396

>NTDB_id=1136584 DQL35_RS08275 WP_111678349.1 1725188..1725937(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIVESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVKVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDD

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1136584 DQL35_RS08275 WP_111678349.1 1725188..1725937(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGCCTCATCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGTGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAAGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

51.6

100

0.518
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386

Multiple sequence alignment