Detailed information NTG1136481

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL15_RS04280
• Genome accession: NZ_LS483323
• Coordinates: 847631..848467 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8300
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 842631..853467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL15_RS04255 (NCTC8300_00846)	-	842850..843842 (-)	993	WP_002989762.1	D-lactate dehydrogenase	-
DQL15_RS04260 (NCTC8300_00847)	-	843857..844423 (-)	567	Protein_761	PTS sugar transporter subunit IIC	-
DQL15_RS09125	-	844463..845320 (+)	858	Protein_762	LysR family transcriptional regulator	-
DQL15_RS04275 (NCTC8300_00849)	topA	845395..847524 (-)	2130	WP_002989768.1	type I DNA topoisomerase	-
DQL15_RS04280 (NCTC8300_00850)	dprA	847631..848467 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
DQL15_RS04285 (NCTC8300_00851)	-	848532..849323 (-)	792	WP_002989771.1	ribonuclease HII	-
DQL15_RS04290 (NCTC8300_00852)	ylqF	849313..850161 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DQL15_RS04295 (NCTC8300_00853)	-	850380..850820 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQL15_RS04300 (NCTC8300_00854)	trhA	850817..851467 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL15_RS04305 (NCTC8300_00855)	-	851584..852495 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
DQL15_RS04310 (NCTC8300_00856)	-	852545..852985 (-)	441	WP_024623381.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=1136481 DQL15_RS04280 WP_002989770.1 847631..848467(-) (dprA) [Streptococcus pyogenes strain NCTC8300]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1136481 DQL15_RS04280 WP_002989770.1 847631..848467(-) (dprA) [Streptococcus pyogenes strain NCTC8300]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367