Detailed information NTG1136368

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL06_RS04900
• Genome accession: NZ_LS483321
• Coordinates: 942463..943299 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8314
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 937463..948299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL06_RS04875 (NCTC8314_00980)	-	937683..938674 (-)	992	Protein_891	D-lactate dehydrogenase	-
DQL06_RS04880 (NCTC8314_00981)	-	938689..939255 (-)	567	Protein_892	PTS sugar transporter subunit IIC	-
DQL06_RS09625	-	939295..940152 (+)	858	Protein_893	LysR family transcriptional regulator	-
DQL06_RS04895 (NCTC8314_00983)	topA	940227..942356 (-)	2130	WP_111689565.1	type I DNA topoisomerase	-
DQL06_RS04900 (NCTC8314_00984)	dprA	942463..943299 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
DQL06_RS04905 (NCTC8314_00985)	-	943364..944155 (-)	792	WP_030125931.1	ribonuclease HII	-
DQL06_RS04910 (NCTC8314_00986)	ylqF	944145..944993 (-)	849	WP_030125932.1	ribosome biogenesis GTPase YlqF	-
DQL06_RS04915 (NCTC8314_00987)	-	945212..945652 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DQL06_RS04920 (NCTC8314_00988)	trhA	945649..946299 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL06_RS04925 (NCTC8314_00989)	-	946416..947327 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
DQL06_RS04930 (NCTC8314_00990)	-	947377..947817 (-)	441	WP_024623381.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=1136368 DQL06_RS04900 WP_002989770.1 942463..943299(-) (dprA) [Streptococcus pyogenes strain NCTC8314]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1136368 DQL06_RS04900 WP_002989770.1 942463..943299(-) (dprA) [Streptococcus pyogenes strain NCTC8314]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367