Detailed information NTG1136069

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL11_RS04600
• Genome accession: NZ_LS483315
• Coordinates: 893283..894119 (-)
• Length: 278 a.a.
• NCBI ID: WP_111704648.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12059
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 888283..899119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL11_RS04575 (NCTC12059_00912)	-	888502..889494 (-)	993	WP_111704646.1	D-lactate dehydrogenase	-
DQL11_RS04580 (NCTC12059_00913)	-	889509..890075 (-)	567	Protein_827	PTS sugar transporter subunit IIC	-
DQL11_RS09185	-	890088..890972 (+)	885	Protein_828	LysR family transcriptional regulator	-
DQL11_RS04595 (NCTC12059_00915)	topA	891047..893176 (-)	2130	WP_111704647.1	type I DNA topoisomerase	-
DQL11_RS04600 (NCTC12059_00916)	dprA	893283..894119 (-)	837	WP_111704648.1	DNA-processing protein DprA	Machinery gene
DQL11_RS04605 (NCTC12059_00917)	-	894184..894975 (-)	792	WP_111704649.1	ribonuclease HII	-
DQL11_RS04610 (NCTC12059_00918)	ylqF	894965..895813 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
DQL11_RS04615 (NCTC12059_00919)	-	896032..896472 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQL11_RS04620 (NCTC12059_00920)	trhA	896469..897119 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQL11_RS04625 (NCTC12059_00921)	-	897236..898147 (+)	912	WP_111704650.1	diacylglycerol/lipid kinase family protein	-
DQL11_RS04630 (NCTC12059_00922)	-	898197..898571 (-)	375	WP_011054498.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.98 Da
• Isoelectric Point: 9.2514

>NTDB_id=1136069 DQL11_RS04600 WP_111704648.1 893283..894119(-) (dprA) [Streptococcus pyogenes strain NCTC12059]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLVTCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1136069 DQL11_RS04600 WP_111704648.1 893283..894119(-) (dprA) [Streptococcus pyogenes strain NCTC12059]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAACAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGGTTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363