Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQL11_RS00665 Genome accession   NZ_LS483315
Coordinates   102516..103550 (+) Length   344 a.a.
NCBI ID   WP_231871968.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12059     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97516..108550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL11_RS00655 (NCTC12059_00132) - 101184..101549 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQL11_RS00660 (NCTC12059_00133) comYA 101642..102580 (+) 939 WP_009880361.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL11_RS00665 (NCTC12059_00134) comYB 102516..103550 (+) 1035 WP_231871968.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL11_RS00670 (NCTC12059_00135) comYC 103552..103878 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL11_RS00675 (NCTC12059_00136) comGD 103853..104281 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  DQL11_RS00680 (NCTC12059_00137) comGE 104238..104522 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  DQL11_RS00685 (NCTC12059_00138) comYF 104515..104949 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL11_RS00690 (NCTC12059_00139) comGG 104933..105259 (+) 327 WP_111704484.1 competence type IV pilus minor pilin ComGG -
  DQL11_RS00695 (NCTC12059_00140) - 105408..106541 (+) 1134 WP_111704485.1 ISAs1-like element IS1548 family transposase -
  DQL11_RS00705 (NCTC12059_00142) comYH 106683..107636 (+) 954 WP_111704832.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39704.20 Da        Isoelectric Point: 9.7085

>NTDB_id=1136041 DQL11_RS00665 WP_231871968.1 102516..103550(+) (comYB) [Streptococcus pyogenes strain NCTC12059]
MISFLRQDISIPSKLSLKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYVLKMEESLLKGQGLADMLSGL
GFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLN
HFPAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDIMAIEKS
SLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQESWEQFFSQLYQVTQLIQPAIFLV
VAVTIVMIYVAILLPIYQNMGGIF

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1136041 DQL11_RS00665 WP_231871968.1 102516..103550(+) (comYB) [Streptococcus pyogenes strain NCTC12059]
TTGATCAGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAGTAAACATCAGCATAA
ATTCATTCAATTACTAGCTAATCTTTTATCTACAGGATTTAGCTTCGCAGAGGTTATTGCTTTTTTAAAAAGAAGCCAGT
TGCTTCAGCTAGATTATGTTCTTAAAATGGAAGAGTCTTTATTAAAAGGACAAGGCTTAGCAGATATGTTGTCGGGTTTA
GGTTTTTCAGATGCTATTCTTACTCAAATTAGTTTAGCTGATAGACACGGTAATATTGAAACAACATTAGTAGCGATTCA
ACATTACTTGAACCAAATGGCAAGGATCAGACGAAAAACTGTTGAAGTTATCACCTATCCTCTTATTCTTTTACTTTTTC
TTTTTGTCATGATGCTAGGGTTGAGACGCTATTTAGTCCCTCAATTAGAAACTCAAAATCAGATAACTTACTTTCTTAAC
CATTTTCCTGCCTTCTTTATAGGTTTTTGCTCAGGTCTTATTTTGTTGTTCGGGATGGTATGGCTACGATGGCGATCTCA
AAGCCGCTTGAAACTCTATAGTCGGCTAAGCCGTTATCCTTTTTTAGGTAAACTGTTAAAACAATACTTAACTAGTTATT
ATGCTAGAGAATGGGGTACGTTAATAGGTCAAGGTCTTGATTTGATGACTATTTTAGACATTATGGCCATTGAGAAATCC
TCACTAATGAAAGAATTAGCTGAGGACATCAGAATGAGTCTGCTTGAAGGGCAAGCCTTTCACATTAAAGTAGCTACCTA
CCCTTTTTTTAAAAAAGAATTAAGTTTAATGATTGAATACGGTGAAATCAAATCGAAACTGGGGGCTGAGTTGGAAATCT
ATGCCCAGGAAAGCTGGGAACAATTTTTTAGTCAGCTTTATCAAGTGACACAACTTATTCAACCAGCTATTTTTTTAGTA
GTTGCTGTGACAATCGTCATGATTTATGTGGCAATCCTATTACCAATTTACCAAAATATGGGAGGTATTTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(28-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.687

98.547

0.529
  comYB Streptococcus mutans UA159

53.687

98.547

0.529
  comYB Streptococcus gordonii str. Challis substr. CH1

50.294

98.837

0.497
  comGB/cglB Streptococcus mitis NCTC 12261

47.321

97.674

0.462
  comGB/cglB Streptococcus mitis SK321

47.447

96.802

0.459
  comGB/cglB Streptococcus pneumoniae Rx1

45.345

96.802

0.439
  comGB/cglB Streptococcus pneumoniae D39

45.345

96.802

0.439
  comGB/cglB Streptococcus pneumoniae R6

45.345

96.802

0.439
  comGB/cglB Streptococcus pneumoniae TIGR4

45.345

96.802

0.439
  comGB Lactococcus lactis subsp. cremoris KW2

42.462

94.477

0.401

Multiple sequence alignment