Detailed information NTG1136044

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: DQL11_RS00705
• Genome accession: NZ_LS483315
• Coordinates: 106683..107636 (+)
• Length: 317 a.a.
• NCBI ID: WP_111704832.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12059
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	105408..106541	106683..107636	flank	142

Gene organization within MGE regions

Location: 105408..107636

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL11_RS00695 (NCTC12059_00140)	-	105408..106541 (+)	1134	WP_111704485.1	ISAs1-like element IS1548 family transposase	-
DQL11_RS00705 (NCTC12059_00142)	comYH	106683..107636 (+)	954	WP_111704832.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 36058.08 Da
• Isoelectric Point: 4.5624

>NTDB_id=1136044 DQL11_RS00705 WP_111704832.1 106683..107636(+) (comYH) [Streptococcus pyogenes strain NCTC12059]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEEASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDEDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide

• Length: 954 bp

>NTDB_id=1136044 DQL11_RS00705 WP_111704832.1 106683..107636(+) (comYH) [Streptococcus pyogenes strain NCTC12059]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGTGCTGAGGAAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAATCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TGAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAAATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-288)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA159	65.506	99.685	0.653
comYH	Streptococcus mutans UA140	65.19	99.685	0.65