Detailed information NTG1135476

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM39_RS05565
• Genome accession: NZ_LS483298
• Coordinates: 1039478..1040314 (-)
• Length: 278 a.a.
• NCBI ID: WP_002984620.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8225
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1034478..1045314

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM39_RS05555 (NCTC8225_01117)	trmFO	1035761..1037107 (-)	1347	WP_011888869.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
DQM39_RS05560 (NCTC8225_01118)	topA	1037242..1039371 (-)	2130	WP_111680858.1	type I DNA topoisomerase	-
DQM39_RS05565 (NCTC8225_01119)	dprA	1039478..1040314 (-)	837	WP_002984620.1	DNA-processing protein DprA	Machinery gene
DQM39_RS05570 (NCTC8225_01120)	-	1040379..1041170 (-)	792	WP_002984622.1	ribonuclease HII	-
DQM39_RS05575 (NCTC8225_01121)	ylqF	1041160..1042008 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
DQM39_RS05580 (NCTC8225_01122)	-	1042227..1042667 (+)	441	WP_002984627.1	DUF1836 domain-containing protein	-
DQM39_RS05585 (NCTC8225_01123)	trhA	1042664..1043314 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQM39_RS05590 (NCTC8225_01124)	-	1043431..1044342 (+)	912	WP_002984631.1	diacylglycerol/lipid kinase family protein	-
DQM39_RS05595 (NCTC8225_01125)	-	1044392..1044832 (-)	441	WP_009880949.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30984.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=1135476 DQM39_RS05565 WP_002984620.1 1039478..1040314(-) (dprA) [Streptococcus pyogenes strain NCTC8225]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCITSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1135476 DQM39_RS05565 WP_002984620.1 1039478..1040314(-) (dprA) [Streptococcus pyogenes strain NCTC8225]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTTCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CATCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.986	100	0.68
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363