Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H1W80_RS07060 Genome accession   NZ_LR822040
Coordinates   1361190..1361885 (-) Length   231 a.a.
NCBI ID   WP_180473307.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1125     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1356190..1366885
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W80_RS07045 (STHERMO_1576) - 1357001..1357546 (-) 546 WP_087010097.1 GNAT family N-acetyltransferase -
  H1W80_RS07050 (STHERMO_1577) - 1357612..1358874 (-) 1263 WP_022096991.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H1W80_RS07055 (STHERMO_1578) - 1358960..1361200 (-) 2241 WP_087010098.1 DNA internalization-related competence protein ComEC/Rec2 -
  H1W80_RS07060 (STHERMO_1579) comEA 1361190..1361885 (-) 696 WP_180473307.1 helix-hairpin-helix domain-containing protein Machinery gene
  H1W80_RS07065 (STHERMO_1580) - 1361993..1362748 (-) 756 WP_023909871.1 lysophospholipid acyltransferase family protein -
  H1W80_RS10025 (STHERMO_1581) - 1362948..1363481 (+) 534 WP_087010099.1 polysaccharide deacetylase family protein -
  H1W80_RS09660 (STHERMO_1582) - 1363415..1363813 (+) 399 WP_414487346.1 peptidoglycan GlcNAc deacetylase -
  H1W80_RS07075 (STHERMO_1583) - 1363863..1364627 (+) 765 WP_180473308.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H1W80_RS07080 (STHERMO_1584) - 1364631..1364900 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24528.49 Da        Isoelectric Point: 4.6300

>NTDB_id=1132012 H1W80_RS07060 WP_180473307.1 1361190..1361885(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_1125]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQISDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1132012 H1W80_RS07060 WP_180473307.1 1361190..1361885(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_1125]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGATCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.701

100

0.987
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372

Multiple sequence alignment