Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H1W87_RS07190 Genome accession   NZ_LR822037
Coordinates   1375185..1375880 (-) Length   231 a.a.
NCBI ID   WP_179966749.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1121     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1370185..1380880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W87_RS07175 (STHERMO_1599) - 1370996..1371541 (-) 546 WP_022096992.1 GNAT family N-acetyltransferase -
  H1W87_RS07180 (STHERMO_1600) - 1371607..1372869 (-) 1263 WP_180478165.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H1W87_RS07185 (STHERMO_1601) - 1372955..1375195 (-) 2241 WP_180478167.1 DNA internalization-related competence protein ComEC/Rec2 -
  H1W87_RS07190 (STHERMO_1602) comEA 1375185..1375880 (-) 696 WP_179966749.1 helix-hairpin-helix domain-containing protein Machinery gene
  H1W87_RS07195 (STHERMO_1603) - 1375988..1376743 (-) 756 WP_002948862.1 lysophospholipid acyltransferase family protein -
  H1W87_RS09775 (STHERMO_1604) - 1376943..1377479 (+) 537 WP_232086644.1 polysaccharide deacetylase family protein -
  H1W87_RS09780 (STHERMO_1605) - 1377520..1377807 (+) 288 WP_096811598.1 peptidoglycan GlcNAc deacetylase -
  H1W87_RS07205 (STHERMO_1606) - 1377857..1378609 (+) 753 WP_002948852.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H1W87_RS07210 (STHERMO_1607) - 1378626..1378895 (+) 270 WP_180478169.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24496.43 Da        Isoelectric Point: 4.6300

>NTDB_id=1131897 H1W87_RS07190 WP_179966749.1 1375185..1375880(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_1121]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGITEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1131897 H1W87_RS07190 WP_179966749.1 1375185..1375880(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_1121]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCAGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAAACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATTACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.701

100

0.987
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372

Multiple sequence alignment