Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H1X13_RS08915 Genome accession   NZ_LR822034
Coordinates   1727923..1729023 (-) Length   366 a.a.
NCBI ID   WP_116920398.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1049     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1722923..1734023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X13_RS10200 (STHERMO_1990) - 1723248..1723523 (-) 276 WP_011681681.1 hypothetical protein -
  H1X13_RS08875 (STHERMO_1991) - 1723535..1723732 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  H1X13_RS08880 (STHERMO_1992) - 1723981..1725174 (-) 1194 WP_096811682.1 acetate kinase -
  H1X13_RS08885 (STHERMO_1993) comYH 1725230..1726186 (-) 957 WP_180481126.1 class I SAM-dependent methyltransferase Machinery gene
  H1X13_RS08890 (STHERMO_1994) comGG 1726231..1726548 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  H1X13_RS08895 (STHERMO_1995) comYF 1726526..1726963 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1X13_RS08900 (STHERMO_1996) comGE 1726947..1727240 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  H1X13_RS08905 (STHERMO_1997) comYD 1727212..1727640 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1X13_RS08910 (STHERMO_1998) comYC 1727600..1727926 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1X13_RS08915 (STHERMO_1999) comYB 1727923..1729023 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1X13_RS08920 (STHERMO_2000) comGA/cglA/cilD 1728905..1729846 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  H1X13_RS08925 (STHERMO_2001) - 1729927..1730289 (-) 363 WP_180481127.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41797.91 Da        Isoelectric Point: 10.1084

>NTDB_id=1131733 H1X13_RS08915 WP_116920398.1 1727923..1729023(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_1049]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1131733 H1X13_RS08915 WP_116920398.1 1727923..1729023(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_1049]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCTAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.678

93.443

0.511
  comYB Streptococcus mutans UA159

54.678

93.443

0.511
  comYB Streptococcus gordonii str. Challis substr. CH1

51.17

93.443

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.453

90.437

0.456
  comGB/cglB Streptococcus mitis SK321

49.697

90.164

0.448
  comGB/cglB Streptococcus pneumoniae Rx1

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae D39

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae R6

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae TIGR4

49.695

89.617

0.445
  comGB Lactococcus lactis subsp. cremoris KW2

45.758

90.164

0.413

Multiple sequence alignment