Detailed information NTG1131730

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H1X13_RS08895
• Genome accession: NZ_LR822034
• Coordinates: 1726526..1726963 (-)
• Length: 145 a.a.
• NCBI ID: WP_011681686.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1049
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1721526..1731963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X13_RS08860 (STHERMO_1987)	-	1721590..1722252 (-)	663	WP_180481124.1	CPBP family intramembrane glutamic endopeptidase	-
H1X13_RS08865 (STHERMO_1988)	-	1722349..1722792 (-)	444	WP_180481125.1	CAAX protease	-
H1X13_RS10195 (STHERMO_1989)	-	1722866..1723204 (-)	339	WP_224103672.1	CPBP family intramembrane glutamic endopeptidase	-
H1X13_RS10200 (STHERMO_1990)	-	1723248..1723523 (-)	276	WP_011681681.1	hypothetical protein	-
H1X13_RS08875 (STHERMO_1991)	-	1723535..1723732 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
H1X13_RS08880 (STHERMO_1992)	-	1723981..1725174 (-)	1194	WP_096811682.1	acetate kinase	-
H1X13_RS08885 (STHERMO_1993)	comYH	1725230..1726186 (-)	957	WP_180481126.1	class I SAM-dependent methyltransferase	Machinery gene
H1X13_RS08890 (STHERMO_1994)	comGG	1726231..1726548 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
H1X13_RS08895 (STHERMO_1995)	comYF	1726526..1726963 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
H1X13_RS08900 (STHERMO_1996)	comGE	1726947..1727240 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H1X13_RS08905 (STHERMO_1997)	comYD	1727212..1727640 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
H1X13_RS08910 (STHERMO_1998)	comYC	1727600..1727926 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H1X13_RS08915 (STHERMO_1999)	comYB	1727923..1729023 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
H1X13_RS08920 (STHERMO_2000)	comGA/cglA/cilD	1728905..1729846 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
H1X13_RS08925 (STHERMO_2001)	-	1729927..1730289 (-)	363	WP_180481127.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.85 Da
• Isoelectric Point: 8.4500

>NTDB_id=1131730 H1X13_RS08895 WP_011681686.1 1726526..1726963(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1049]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1131730 H1X13_RS08895 WP_011681686.1 1726526..1726963(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1049]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTTAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae Rx1	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae R6	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae TIGR4	49.286	96.552	0.476
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.809	97.241	0.455
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434