Detailed information NTG1131607

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H1W91_RS08890
• Genome accession: NZ_LR822032
• Coordinates: 1707906..1708343 (-)
• Length: 145 a.a.
• NCBI ID: WP_082309153.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1050
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1702906..1713343

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W91_RS08855 (STHERMO_1961)	-	1702972..1703634 (-)	663	WP_180477177.1	CPBP family intramembrane glutamic endopeptidase	-
H1W91_RS08860 (STHERMO_1962)	-	1703731..1704173 (-)	443	Protein_1691	CAAX protease	-
H1W91_RS10205 (STHERMO_1963)	-	1704247..1704672 (-)	426	WP_111679733.1	CPBP family intramembrane glutamic endopeptidase	-
H1W91_RS08870 (STHERMO_1965)	-	1704915..1705112 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
H1W91_RS08875 (STHERMO_1966)	-	1705361..1706554 (-)	1194	WP_014608740.1	acetate kinase	-
H1W91_RS08880 (STHERMO_1967)	comYH	1706610..1707566 (-)	957	WP_180477178.1	class I SAM-dependent methyltransferase	Machinery gene
H1W91_RS08885 (STHERMO_1968)	comGG	1707611..1707928 (-)	318	WP_180477179.1	competence type IV pilus minor pilin ComGG	-
H1W91_RS08890 (STHERMO_1969)	comYF	1707906..1708343 (-)	438	WP_082309153.1	competence type IV pilus minor pilin ComGF	Machinery gene
H1W91_RS08895 (STHERMO_1970)	comGE	1708327..1708620 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
H1W91_RS08900 (STHERMO_1971)	comGD	1708592..1709020 (-)	429	WP_253269448.1	competence type IV pilus minor pilin ComGD	-
H1W91_RS08905 (STHERMO_1972)	comYC	1708980..1709306 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H1W91_RS08910 (STHERMO_1973)	comYB	1709303..1710403 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
H1W91_RS08915 (STHERMO_1974)	comGA/cglA/cilD	1710285..1711226 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
H1W91_RS08920 (STHERMO_1975)	-	1711307..1711669 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16423.93 Da
• Isoelectric Point: 8.9531

>NTDB_id=1131607 H1W91_RS08890 WP_082309153.1 1707906..1708343(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1050]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQYLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1131607 H1W91_RS08890 WP_082309153.1 1707906..1708343(-) (comYF) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGTATCTAAGCAGTAAGTTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCAGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAATACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434