Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H1W91_RS07460 Genome accession   NZ_LR822032
Coordinates   1430223..1430918 (-) Length   231 a.a.
NCBI ID   WP_180477115.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1050     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1425223..1435918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W91_RS07445 (STHERMO_1630) - 1426034..1426579 (-) 546 WP_180477113.1 GNAT family N-acetyltransferase -
  H1W91_RS07450 (STHERMO_1631) - 1426645..1427907 (-) 1263 WP_022096991.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H1W91_RS07455 (STHERMO_1632) - 1427993..1430233 (-) 2241 WP_180477114.1 DNA internalization-related competence protein ComEC/Rec2 -
  H1W91_RS07460 (STHERMO_1633) comEA 1430223..1430918 (-) 696 WP_180477115.1 helix-hairpin-helix domain-containing protein Machinery gene
  H1W91_RS07465 (STHERMO_1634) - 1431026..1431781 (-) 756 WP_180477116.1 lysophospholipid acyltransferase family protein -
  H1W91_RS07470 (STHERMO_1635) - 1431970..1432836 (+) 867 WP_311316651.1 polysaccharide deacetylase family protein -
  H1W91_RS07475 (STHERMO_1636) - 1432852..1434090 (-) 1239 Protein_1417 ISL3-like element ISSth1 family transposase -
  H1W91_RS07480 (STHERMO_1637) - 1434319..1435071 (+) 753 WP_180477117.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H1W91_RS07485 (STHERMO_1638) - 1435088..1435357 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24528.49 Da        Isoelectric Point: 4.6300

>NTDB_id=1131597 H1W91_RS07460 WP_180477115.1 1430223..1430918(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_1050]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDIIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1131597 H1W91_RS07460 WP_180477115.1 1430223..1430918(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_1050]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TATCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.701

100

0.987
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372

Multiple sequence alignment