Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   H1W91_RS04575 Genome accession   NZ_LR822032
Coordinates   870871..873018 (-) Length   715 a.a.
NCBI ID   WP_095559353.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1050     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 865871..878018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W91_RS04545 (STHERMO_0987) cas1 866090..867094 (+) 1005 WP_180476960.1 CRISPR-associated endonuclease Cas1 -
  H1W91_RS04550 (STHERMO_0988) cas2 867094..867423 (+) 330 WP_014608281.1 CRISPR-associated endonuclease Cas2 -
  H1W91_RS04555 (STHERMO_0989) - 867854..868276 (+) 423 WP_095559351.1 ribosomal RNA small subunit methyltransferase A -
  H1W91_RS04560 (STHERMO_0990) comB 868311..868799 (-) 489 WP_415669573.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  H1W91_RS04565 (STHERMO_0991) - 869005..869430 (+) 426 Protein_845 ribosomal RNA small subunit methyltransferase A -
  H1W91_RS04570 (STHERMO_0992) - 869465..870859 (-) 1395 WP_095559352.1 bacteriocin secretion accessory protein -
  H1W91_RS04575 (STHERMO_0993) comA/nlmT 870871..873018 (-) 2148 WP_095559353.1 peptide cleavage/export ABC transporter Regulator
  H1W91_RS04580 (STHERMO_0994) - 873293..873514 (+) 222 WP_101415610.1 Blp family class II bacteriocin -
  H1W91_RS04585 (STHERMO_0995) - 873566..873793 (+) 228 WP_058621356.1 bacteriocin class II family protein -
  H1W91_RS04590 (STHERMO_0996) - 873815..874198 (+) 384 WP_095559354.1 hypothetical protein -
  H1W91_RS04595 - 874195..874398 (+) 204 Protein_851 garvicin Q family class II bacteriocin -
  H1W91_RS04600 (STHERMO_0997) - 874410..874712 (+) 303 WP_015695689.1 bacteriocin immunity protein -
  H1W91_RS04605 (STHERMO_0998) - 874870..875103 (+) 234 WP_095559355.1 Blp family class II bacteriocin -
  H1W91_RS04610 (STHERMO_0999) - 875293..875550 (+) 258 WP_095559356.1 garvicin Q family class II bacteriocin -
  H1W91_RS04615 (STHERMO_1000) - 875550..875858 (+) 309 WP_018364976.1 bacteriocin immunity protein -
  H1W91_RS04620 (STHERMO_1001) - 876233..876412 (+) 180 WP_095559357.1 hypothetical protein -
  H1W91_RS04625 (STHERMO_1002) - 876654..876854 (+) 201 WP_006531882.1 bacteriocin class II family protein -
  H1W91_RS04630 (STHERMO_1003) - 876880..877062 (+) 183 WP_006531883.1 Blp family class II bacteriocin -
  H1W91_RS04635 (STHERMO_1004) - 877679..877909 (+) 231 WP_043878356.1 bacteriocin -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 80092.91 Da        Isoelectric Point: 7.0609

>NTDB_id=1131582 H1W91_RS04575 WP_095559353.1 870871..873018(-) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_1050]
MRRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKAIGFETRAIQANMELFDMADIPY
PFIVHVNKEGKLQHYYVVYKAKKNHLIIGDPDPSVKVTKMPKERFEKEWTGVAIFLAPAPHYQPHKDKKNGLTSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNHLQSTLGIVSVGLIVTYIMQQIMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNANLFFITLIALPIYAIII
LAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEEVRYQNIDREFVDYLDKSFTLSKYEAVQTSLKQGAQLIL
NVAILWYGSHLVMAGNISVGQLITYNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDGKQLLNDSHFLQG
DIVFDDVSYKYGFGRDTLSHVNLHIKKGEKISLVGISGSGKTTLAKMIVNFYTPNHGQITLGGYDLKTIDKKAIRQYINY
LPQQSYVFSGTILENLTLGAPDNITQEEILKACEIAEIRADIELMPLAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDVLTEKRVIKNLLSLTDKTIIFVAHRLSIAEQSDRVIVLDKGQVIEEGHHKQLIQNQGFYAQLFHE

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=1131582 H1W91_RS04575 WP_095559353.1 870871..873018(-) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGAGGAGATACAAGTATGTTAGTCAGATTGATTTGCGAGATTGTGGTGTGGCAGCTTTGGCGTCAGTTGCCAAGCATTA
TGGATCTGATTTCTCACTGGCACACCTAAGGGAATTAGCTAAAACAACTAAGGAAGGGACGACAGCGTTAGGGATAGTCG
AGGCAGCTAAAGCCATTGGCTTTGAAACACGCGCCATTCAAGCTAACATGGAACTGTTTGATATGGCCGATATTCCCTAT
CCTTTTATTGTTCATGTTAACAAAGAAGGCAAACTGCAGCACTATTATGTCGTTTACAAAGCTAAGAAAAACCACCTTAT
CATCGGTGATCCAGACCCCAGTGTCAAAGTGACCAAAATGCCCAAGGAGCGCTTTGAAAAGGAATGGACAGGTGTCGCCA
TTTTCTTAGCACCTGCTCCGCATTATCAACCGCATAAAGATAAGAAAAATGGCTTAACAAGCTTTTTACCAATTATTTTC
AAACAAAAGGCACTGCTAACTTATATCATTCTGGCAAGTTTGCTCGTGACCTTGATTAACATTGTTGGGTCTTACTATTT
GCAAGGAATCTTAGACGATTATATTCCTAATCATTTGCAATCCACTCTTGGCATTGTCTCGGTTGGGTTGATTGTAACCT
ACATAATGCAACAAATCATGAGCTTTTCACAAAATTATTTACTTGTTGTGCTGAGCCAACGGTTAACAATTGACGTGATT
TTGTCTTATATTCGTCACATTTTTGAATTGCCCATGTCTTTTTTTGCCACAAGGCGGACAGGTGAAGTGATCTCACGTTT
CACCGATGCTAACTCGATTATTGATGCACTGGCATCAACGATTCTCTCTTTATTTTTAGATGTGAGTATTTTGTTTATTG
TCGGAAGTGTCTTAATTCTGCAAAATGCCAATCTCTTTTTCATCACCTTAATAGCATTGCCTATCTATGCTATTATTATT
TTGGCTTTTATGAAGCCTTTTGAGCGAATGAATCACGATGTCATGCAAGCCAATTCTATGGTTAGCTCTGCGATTATCGA
AGATATCAATGGTATTGAAACGATTAAATCTTTGACTAGTGAGGAAGTCCGTTATCAAAATATTGACCGTGAATTTGTGG
ATTATTTGGATAAAAGTTTTACGCTTAGTAAGTATGAAGCTGTGCAAACGTCGTTAAAACAGGGAGCACAGCTAATTTTA
AACGTCGCTATTCTCTGGTATGGTTCACATTTAGTCATGGCTGGGAACATTTCAGTAGGTCAATTGATTACTTACAATAC
GCTTCTGTCGTACTTTACAACACCAATGGAAAATATTATTAATCTGCAAACCAAACTACAATCTGCCAAAGTAGCTAACA
ATCGTCTCAACGAAGTTTACTTAGTGTCATCTGAATTTGATGGCAAACAACTCTTAAATGACAGCCATTTTCTACAAGGA
GATATTGTTTTTGATGATGTTTCTTATAAATATGGTTTTGGTCGTGACACGCTGAGTCATGTGAATTTACACATTAAGAA
AGGTGAAAAAATTAGCCTAGTTGGTATCAGCGGTTCTGGTAAGACAACCTTAGCTAAAATGATTGTCAATTTTTACACAC
CTAACCATGGACAGATTACCCTTGGTGGCTACGATTTAAAAACCATTGATAAAAAAGCCATTCGCCAATACATTAATTAC
CTACCACAACAGTCTTACGTCTTTTCAGGGACGATTTTAGAAAATTTAACCTTGGGAGCACCTGACAATATCACGCAAGA
AGAAATTCTGAAAGCTTGTGAAATCGCTGAAATCCGTGCTGATATTGAATTGATGCCACTAGCATACCATACCGAACTTT
CAGATGGTGCTGGGTTATCTGGTGGGCAAAAGCAACGTTTAGCTTTAGCACGCGCTTTACTGACACAAGCTCCCGTCTTG
ATTTTAGATGAAGCCACAAGTGGTCTTGATGTTCTAACGGAAAAACGTGTGATTAAAAATTTACTATCTCTCACAGACAA
AACTATTATTTTTGTTGCCCACCGTTTGAGCATTGCTGAACAATCTGACCGTGTCATTGTTCTAGATAAAGGACAAGTTA
TCGAAGAAGGGCATCATAAACAACTCATCCAAAATCAAGGTTTCTATGCACAGTTATTTCATGAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-140)

ABC transporter transmembrane region (ABC_membrane)

(166-436)

ABC transporter (ABC_tran)

(498-647)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.827

99.72

0.706
  comA Streptococcus mitis NCTC 12261

67.465

99.301

0.67
  comA Streptococcus pneumoniae D39

67.232

99.021

0.666
  comA Streptococcus pneumoniae R6

67.232

99.021

0.666
  comA Streptococcus pneumoniae Rx1

67.232

99.021

0.666
  comA Streptococcus mitis SK321

66.901

99.301

0.664
  comA Streptococcus gordonii str. Challis substr. CH1

66.48

99.72

0.663
  comA Streptococcus pneumoniae TIGR4

66.949

99.021

0.663

Multiple sequence alignment