Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   H1W91_RS04560 Genome accession   NZ_LR822032
Coordinates   868311..868799 (-) Length   162 a.a.
NCBI ID   WP_415669573.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1050     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 863311..873799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W91_RS04525 (STHERMO_0984) - 863393..863941 (+) 549 WP_011225930.1 DJ-1 family glyoxalase III -
  H1W91_RS04530 - 863998..864213 (-) 216 WP_011681107.1 hypothetical protein -
  H1W91_RS04535 (STHERMO_0985) - 864212..864985 (+) 774 WP_232087079.1 dihydroorotate dehydrogenase electron transfer subunit -
  H1W91_RS04540 (STHERMO_0986) - 864995..865951 (+) 957 WP_180476959.1 dihydroorotate dehydrogenase -
  H1W91_RS04545 (STHERMO_0987) cas1 866090..867094 (+) 1005 WP_180476960.1 CRISPR-associated endonuclease Cas1 -
  H1W91_RS04550 (STHERMO_0988) cas2 867094..867423 (+) 330 WP_014608281.1 CRISPR-associated endonuclease Cas2 -
  H1W91_RS04555 (STHERMO_0989) - 867854..868276 (+) 423 WP_095559351.1 ribosomal RNA small subunit methyltransferase A -
  H1W91_RS04560 (STHERMO_0990) comB 868311..868799 (-) 489 WP_415669573.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  H1W91_RS04565 (STHERMO_0991) - 869005..869430 (+) 426 Protein_845 ribosomal RNA small subunit methyltransferase A -
  H1W91_RS04570 (STHERMO_0992) - 869465..870859 (-) 1395 WP_095559352.1 bacteriocin secretion accessory protein -
  H1W91_RS04575 (STHERMO_0993) comA/nlmT 870871..873018 (-) 2148 WP_095559353.1 peptide cleavage/export ABC transporter Regulator
  H1W91_RS04580 (STHERMO_0994) - 873293..873514 (+) 222 WP_101415610.1 Blp family class II bacteriocin -
  H1W91_RS04585 (STHERMO_0995) - 873566..873793 (+) 228 WP_058621356.1 bacteriocin class II family protein -

Sequence

Protein


Download         Length: 162 a.a.        Molecular weight: 18016.59 Da        Isoelectric Point: 10.2019

>NTDB_id=1131581 H1W91_RS04560 WP_415669573.1 868311..868799(-) (comB) [Streptococcus thermophilus isolate STH_CIRM_1050]
MRSTRFRPLSQLDQTNLSKADTVLKASQSGILHVSDEFEGQTLLPQGSQIAEIYPDIAKTQQVAIRYYVDSTHVSQLKKG
QTVRLTLEKISNHAIVITGKISKIASSATQTKEGNVFEVTALATVDKQDSSKLKYGLQGKTISTIGKKTFFNYYKDKLLK
DF

Nucleotide


Download         Length: 489 bp        

>NTDB_id=1131581 H1W91_RS04560 WP_415669573.1 868311..868799(-) (comB) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATACGAAGCACGCGTTTCCGTCCCCTCTCGCAGCTTGACCAGACAAATCTCTCCAAAGCTGACACCGTTTTAAAAGCTAG
TCAAAGTGGCATTTTACATGTTTCTGATGAATTTGAAGGGCAAACGCTCTTGCCGCAAGGCAGTCAGATTGCAGAGATTT
ACCCAGATATTGCCAAAACACAGCAAGTCGCTATCCGCTATTACGTTGACTCCACTCATGTTAGTCAATTGAAAAAAGGA
CAGACTGTTCGCCTAACCCTTGAAAAAATTAGCAATCACGCCATTGTTATCACTGGCAAAATCAGTAAAATTGCAAGTTC
TGCCACACAAACCAAAGAAGGAAATGTCTTTGAGGTGACAGCACTAGCCACCGTTGATAAACAAGATAGCTCCAAATTGA
AATATGGTTTACAAGGCAAAACAATCAGCACTATCGGCAAAAAAACTTTCTTTAATTATTACAAAGACAAGCTATTAAAA
GATTTTTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(23-136)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mutans UA159

58.955

82.716

0.488
  comB/nlmE Streptococcus mutans UA159

52.985

82.716

0.438
  comB Streptococcus gordonii str. Challis substr. CH1

39.073

93.21

0.364

Multiple sequence alignment