Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H1W74_RS07025 Genome accession   NZ_LR822031
Coordinates   1362698..1363393 (-) Length   231 a.a.
NCBI ID   WP_022096989.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1363522..1368344 1362698..1363393 flank 129


Gene organization within MGE regions


Location: 1362698..1368344
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS07025 (STHERMO_1594) comEA 1362698..1363393 (-) 696 WP_022096989.1 helix-hairpin-helix domain-containing protein Machinery gene
  H1W74_RS07035 (STHERMO_1597) - 1365189..1365944 (-) 756 WP_002948862.1 lysophospholipid acyltransferase family protein -
  H1W74_RS10210 (STHERMO_1598) - 1366144..1366677 (+) 534 WP_002948860.1 polysaccharide deacetylase family protein -
  H1W74_RS09845 (STHERMO_1599) - 1366611..1367000 (+) 390 WP_288217394.1 peptidoglycan GlcNAc deacetylase -
  H1W74_RS07045 (STHERMO_1600) - 1367016..1368272 (-) 1257 Protein_1348 ISL3-like element ISSth1 family transposase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24572.50 Da        Isoelectric Point: 4.5661

>NTDB_id=1131536 H1W74_RS07025 WP_022096989.1 1362698..1363393(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_1047]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKEGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1131536 H1W74_RS07025 WP_022096989.1 1362698..1363393(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_1047]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGAAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGTAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCAGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.701

100

0.987
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372

Multiple sequence alignment