Detailed information NTG1131467

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: H1W95_RS05340
• Genome accession: NZ_LR822030
• Coordinates: 1034682..1035389 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1046
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1029682..1040389

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W95_RS05315 (STHERMO_1183)	yidA	1030033..1030842 (+)	810	WP_011226081.1	sugar-phosphatase	-
H1W95_RS05320 (STHERMO_1184)	-	1030844..1032058 (+)	1215	WP_004197368.1	aminoacyltransferase	-
H1W95_RS05325 (STHERMO_1185)	-	1032110..1032471 (-)	362	Protein_1004	YbaN family protein	-
H1W95_RS05330 (STHERMO_1186)	vicX	1032531..1033343 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
H1W95_RS05335 (STHERMO_1187)	vicK	1033349..1034689 (-)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H1W95_RS05340 (STHERMO_1188)	vicR	1034682..1035389 (-)	708	WP_011681206.1	response regulator YycF	Regulator
H1W95_RS05345 (STHERMO_1189)	-	1035916..1036683 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
H1W95_RS05350 (STHERMO_1190)	-	1036695..1037528 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
H1W95_RS05355 (STHERMO_1191)	-	1037546..1038244 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
H1W95_RS05360 (STHERMO_1192)	-	1038256..1038906 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
H1W95_RS05365 (STHERMO_1193)	endA	1038978..1039859 (-)	882	WP_180483255.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W95_RS05370 (STHERMO_1194)	-	1039921..1040109 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=1131467 H1W95_RS05340 WP_011681206.1 1034682..1035389(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_1046]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1131467 H1W95_RS05340 WP_011681206.1 1034682..1035389(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_1046]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387