Detailed information NTG1131464

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H1W95_RS04370
• Genome accession: NZ_LR822030
• Coordinates: 849459..850298 (+)
• Length: 279 a.a.
• NCBI ID: WP_180483583.1
• Uniprot ID: A0AAU9HA00
• Organism: Streptococcus thermophilus isolate STH_CIRM_1046
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 844459..855298

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W95_RS04340 (STHERMO_0949)	-	844875..845402 (+)	528	WP_011681081.1	ECF transporter S component	-
H1W95_RS04345 (STHERMO_0950)	-	845426..845941 (+)	516	WP_014621521.1	transcription repressor NadR	-
H1W95_RS04350 (STHERMO_0951)	-	846036..846725 (+)	690	WP_014621522.1	XRE family transcriptional regulator	-
H1W95_RS04355 (STHERMO_0952)	ylqF	846853..847707 (+)	855	WP_002950602.1	ribosome biogenesis GTPase YlqF	-
H1W95_RS04360 (STHERMO_0953)	-	847694..848461 (+)	768	WP_064355754.1	ribonuclease HII	-
H1W95_RS04365 (STHERMO_0954)	-	848472..849392 (+)	921	WP_014608255.1	ROK family protein	-
H1W95_RS04370 (STHERMO_0955)	dprA	849459..850298 (+)	840	WP_180483583.1	DNA-processing protein DprA	Machinery gene
H1W95_RS04375 (STHERMO_0957)	topA	850466..852610 (+)	2145	WP_064355758.1	type I DNA topoisomerase	-
H1W95_RS04380 (STHERMO_0958)	-	852727..853551 (+)	825	WP_014608257.1	TraX family protein	-
H1W95_RS04385 (STHERMO_0959)	-	853587..854246 (+)	660	WP_011227158.1	response regulator transcription factor	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31231.18 Da
• Isoelectric Point: 8.6643

>NTDB_id=1131464 H1W95_RS04370 WP_180483583.1 849459..850298(+) (dprA) [Streptococcus thermophilus isolate STH_CIRM_1046]
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAVLFMEKYKNLDVKQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVHELGNAFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKFHYPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDIISEFS

Nucleotide

• Length: 840 bp

>NTDB_id=1131464 H1W95_RS04370 WP_180483583.1 849459..850298(+) (dprA) [Streptococcus thermophilus isolate STH_CIRM_1046]
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTAACGAATTTAAACATCCTTAACATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCCGTTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAAGCAGCTTAAGGAAGATTTTCAACGTTTTCCGACCTTATCAATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTCCTCCTCTTTTATCAAGGGAATATTGATTTGCTAAGTAAACCCAAGTT
AGCGGTAGTTGGTGCCAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTTCGAAAAATTGTTCATGAACTTGGGAATGCCT
TTACTATTGTAAGTGGCTTGGCGCGTGGAATTGATACTTGTGCTCATATGGAGGCCTTAAAAAATAAAGGTAACACCATT
GCAGTTATCGGGACTGGGCTAGACGTATATTATCCTAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTACAGAATACGGACCGGGTGAACAGCCACTTAAATTCCATTATCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGGGTTATGGTGGTTGAAGCCAAGCTTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGAAGA
GATGTTTTCGCCATACCAGGAAATATTTTAGATGGAAAATCGGATGGATGCCATCACCTCATTCAAGAGGGCGCAAAGTG
CATTACTACAGGATTTGACATCATTTCAGAATTTTCATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	71.685	100	0.717
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.669	99.642	0.634
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.669	99.642	0.634
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.669	99.642	0.634
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.669	99.642	0.634
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus mitis SK321	63.309	99.642	0.631
dprA	Lactococcus lactis subsp. cremoris KW2	60.072	99.642	0.599
dprA	Latilactobacillus sakei subsp. sakei 23K	39.382	92.832	0.366
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75.269	0.362