Detailed information NTG1131409

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H1W89_RS05305
• Genome accession: NZ_LR822029
• Coordinates: 1005939..1006778 (-)
• Length: 279 a.a.
• NCBI ID: WP_180474556.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1035
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1000939..1011778

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W89_RS05290 (STHERMO_1156)	-	1001991..1002650 (-)	660	WP_011227158.1	response regulator transcription factor	-
H1W89_RS05295 (STHERMO_1157)	-	1002686..1003510 (-)	825	WP_014608257.1	TraX family protein	-
H1W89_RS05300 (STHERMO_1158)	topA	1003627..1005771 (-)	2145	WP_014608256.1	type I DNA topoisomerase	-
H1W89_RS05305 (STHERMO_1159)	dprA	1005939..1006778 (-)	840	WP_180474556.1	DNA-processing protein DprA	Machinery gene
H1W89_RS05310 (STHERMO_1160)	-	1006845..1007765 (-)	921	WP_014608255.1	ROK family protein	-
H1W89_RS05315 (STHERMO_1161)	-	1007776..1008543 (-)	768	WP_002950603.1	ribonuclease HII	-
H1W89_RS05320 (STHERMO_1162)	ylqF	1008530..1009384 (-)	855	WP_002950602.1	ribosome biogenesis GTPase YlqF	-
H1W89_RS05325 (STHERMO_1163)	-	1009512..1010201 (-)	690	WP_180474557.1	helix-turn-helix transcriptional regulator	-
H1W89_RS05330 (STHERMO_1164)	-	1010296..1010811 (-)	516	WP_014621521.1	transcription repressor NadR	-
H1W89_RS05335 (STHERMO_1165)	-	1010835..1011362 (-)	528	WP_011681081.1	ECF transporter S component	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31293.27 Da
• Isoelectric Point: 8.5481

>NTDB_id=1131409 H1W89_RS05305 WP_180474556.1 1005939..1006778(-) (dprA) [Streptococcus thermophilus isolate STH_CIRM_1035]
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAVLFMEKYKNLDVKQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVHELGNAFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPCEQPLKYHYPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDIISEFS

Nucleotide

• Length: 840 bp

>NTDB_id=1131409 H1W89_RS05305 WP_180474556.1 1005939..1006778(-) (dprA) [Streptococcus thermophilus isolate STH_CIRM_1035]
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTAACGAATTTAAACATCCTTAACATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCCGTTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAAGCAGCTTAAGGAAGATTTTCAACGTTTTCCGACCTTATCAATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTCCTCCTCTTTTATCAAGGGAATATTGATTTGCTAAGTAAACCCAAGTT
AGCGGTAGTTGGTGCCAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTTCGAAAAATTGTTCATGAACTTGGGAATGCCT
TTACTATTGTAAGTGGCTTGGCGCGTGGAATTGATACTTGTGCTCATATGGAGGCCTTAAAAAATAAAGGTAACACCATT
GCAGTTATCGGGACTGGGCTAGACGTATATTATCCTAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTACAGAATACGGACCGTGTGAACAGCCACTTAAATACCATTATCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGGGTTATGGTGGTTGAAGCCAAGCTTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGAAGA
GATGTTTTCGCCATACCAGGAAATATTTTAGATGGAAAATCGGATGGATGCCATCACCTCATTCAAGAGGGCGCAAAGTG
CATTACTACAGGATTTGACATCATTTCAGAATTTTCATAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	72.043	100	0.72
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus pneumoniae D39	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus pneumoniae R6	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.59	99.642	0.624
dprA/cilB/dalA	Streptococcus mitis SK321	62.59	99.642	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	60.072	99.642	0.599
dprA	Latilactobacillus sakei subsp. sakei 23K	39.382	92.832	0.366
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75.269	0.362