Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H0513_RS09580 Genome accession   NZ_LR822023
Coordinates   1834287..1835387 (-) Length   366 a.a.
NCBI ID   WP_179973038.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_368     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1829287..1840387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0513_RS11610 (STHERMO_2165) - 1829447..1829888 (-) 442 Protein_1812 CAAX protease -
  H0513_RS09540 (STHERMO_2166) - 1829900..1830097 (-) 198 WP_179972339.1 helix-turn-helix transcriptional regulator -
  H0513_RS09545 (STHERMO_2167) - 1830345..1831538 (-) 1194 WP_179972340.1 acetate kinase -
  H0513_RS09550 (STHERMO_2168) comYH 1831594..1832550 (-) 957 WP_179972341.1 class I SAM-dependent methyltransferase Machinery gene
  H0513_RS09555 (STHERMO_2169) comGG 1832601..1832912 (-) 312 WP_179972342.1 competence type IV pilus minor pilin ComGG -
  H0513_RS09560 (STHERMO_2170) comYF 1832890..1833327 (-) 438 WP_179972343.1 competence type IV pilus minor pilin ComGF Machinery gene
  H0513_RS09565 (STHERMO_2171) comGE 1833311..1833604 (-) 294 WP_179972344.1 competence type IV pilus minor pilin ComGE -
  H0513_RS09570 (STHERMO_2172) comGD 1833576..1834004 (-) 429 WP_269473123.1 competence type IV pilus minor pilin ComGD -
  H0513_RS09575 (STHERMO_2173) comYC 1833964..1834290 (-) 327 WP_179972346.1 competence type IV pilus major pilin ComGC Machinery gene
  H0513_RS09580 (STHERMO_2174) comYB 1834287..1835387 (-) 1101 WP_179973038.1 competence type IV pilus assembly protein ComGB Machinery gene
  H0513_RS09585 (STHERMO_2175) comGA/cglA/cilD 1835269..1836210 (-) 942 WP_179972347.1 competence type IV pilus ATPase ComGA Machinery gene
  H0513_RS09590 (STHERMO_2176) - 1836291..1836653 (-) 363 WP_179972348.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 42075.24 Da        Isoelectric Point: 10.1295

>NTDB_id=1131181 H0513_RS09580 WP_179973038.1 1834287..1835387(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_368]
MPEKISKTIRRPTGIISWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLDQMFALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMIGLKN
YLLPQLLEGDGRNNWAVQLVQIFPQLFFVSLCRFLVLGLILYLWVKRQSALVFYRRMAQIPFIGQIVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIIAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1131181 H0513_RS09580 WP_179973038.1 1834287..1835387(-) (comYB) [Streptococcus thermophilus isolate STH_CIRM_368]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCATCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTCTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACGTCCTTGTCTCTTATG
AAGGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTCGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTAGGTTTTCTGATTCTGATTATGATAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAGGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCTCAGCTCTT
TTTTGTGAGTTTGTGTAGATTCCTTGTGTTGGGCTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCCAAATCCCTTTTATTGGTCAGATAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCGCTAATTATTGCTTATGGAGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTATTGCAGTTGTGATTGT
GATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.386

93.443

0.508
  comYB Streptococcus mutans UA159

54.386

93.443

0.508
  comYB Streptococcus gordonii str. Challis substr. CH1

50.877

93.443

0.475
  comGB/cglB Streptococcus mitis NCTC 12261

49.849

90.437

0.451
  comGB/cglB Streptococcus mitis SK321

49.091

90.164

0.443
  comGB/cglB Streptococcus pneumoniae Rx1

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae D39

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae R6

49.085

89.617

0.44
  comGB/cglB Streptococcus pneumoniae TIGR4

49.085

89.617

0.44
  comGB Lactococcus lactis subsp. cremoris KW2

43.769

89.891

0.393

Multiple sequence alignment