Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   H0513_RS09550 Genome accession   NZ_LR822023
Coordinates   1831594..1832550 (-) Length   318 a.a.
NCBI ID   WP_179972341.1    Uniprot ID   A0A7U7CBK4
Organism   Streptococcus thermophilus isolate STH_CIRM_368     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1826594..1837550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0513_RS09525 (STHERMO_2161) pepA 1826805..1827872 (+) 1068 WP_179972336.1 glutamyl aminopeptidase -
  H0513_RS09530 (STHERMO_2162) proC 1827888..1828658 (+) 771 WP_179972337.1 pyrroline-5-carboxylate reductase -
  H0513_RS09535 (STHERMO_2163) - 1828688..1829350 (-) 663 WP_179972338.1 CPBP family intramembrane glutamic endopeptidase -
  H0513_RS11610 (STHERMO_2165) - 1829447..1829888 (-) 442 Protein_1812 CAAX protease -
  H0513_RS09540 (STHERMO_2166) - 1829900..1830097 (-) 198 WP_179972339.1 helix-turn-helix transcriptional regulator -
  H0513_RS09545 (STHERMO_2167) - 1830345..1831538 (-) 1194 WP_179972340.1 acetate kinase -
  H0513_RS09550 (STHERMO_2168) comYH 1831594..1832550 (-) 957 WP_179972341.1 class I SAM-dependent methyltransferase Machinery gene
  H0513_RS09555 (STHERMO_2169) comGG 1832601..1832912 (-) 312 WP_179972342.1 competence type IV pilus minor pilin ComGG -
  H0513_RS09560 (STHERMO_2170) comYF 1832890..1833327 (-) 438 WP_179972343.1 competence type IV pilus minor pilin ComGF Machinery gene
  H0513_RS09565 (STHERMO_2171) comGE 1833311..1833604 (-) 294 WP_179972344.1 competence type IV pilus minor pilin ComGE -
  H0513_RS09570 (STHERMO_2172) comGD 1833576..1834004 (-) 429 WP_269473123.1 competence type IV pilus minor pilin ComGD -
  H0513_RS09575 (STHERMO_2173) comYC 1833964..1834290 (-) 327 WP_179972346.1 competence type IV pilus major pilin ComGC Machinery gene
  H0513_RS09580 (STHERMO_2174) comYB 1834287..1835387 (-) 1101 WP_179973038.1 competence type IV pilus assembly protein ComGB Machinery gene
  H0513_RS09585 (STHERMO_2175) comGA/cglA/cilD 1835269..1836210 (-) 942 WP_179972347.1 competence type IV pilus ATPase ComGA Machinery gene
  H0513_RS09590 (STHERMO_2176) - 1836291..1836653 (-) 363 WP_179972348.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35987.11 Da        Isoelectric Point: 4.6574

>NTDB_id=1131178 H0513_RS09550 WP_179972341.1 1831594..1832550(-) (comYH) [Streptococcus thermophilus isolate STH_CIRM_368]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANELIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTQEKQLDILEIGSGTGNLAETLLNNTQRTLNYMGMEVDDLLIDLSASIAEVVNSV
AVYIQEDAVRPHILKESNVIISDLPIGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAIFLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFSNKHNMKSIFVLKKQTKNAPETFVYPLSDLQNPRVLKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=1131178 H0513_RS09550 WP_179972341.1 1831594..1832550(-) (comYH) [Streptococcus thermophilus isolate STH_CIRM_368]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACTATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTTGCTAATGAGCTCATCATCAAAAACAACG
AGAAATTACGGGCGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTTTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATCGGATTTATCATTCTGTACTTGCTCGAAGGTTTGACCCA
GGAAAAACAATTGGATATCTTGGAGATTGGTTCGGGAACAGGGAACTTGGCTGAAACTCTTCTAAATAATACTCAGAGAA
CCCTTAATTATATGGGGATGGAAGTTGATGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGAGGTGGTAAATTCAGTA
GCGGTTTATATCCAAGAGGATGCTGTTCGACCACATATTCTCAAAGAGAGTAACGTTATTATCAGCGATTTACCTATAGG
TTACTACCCTAATGATGAGATTGCGAGTCGTTTCAAGGTGGCAGCAACCGGCGAACACACTTATGCCCATCATCTTCTTA
TGGAGCAATCGCTTAAGTATTTGAAGAAAGATGGTATTGCTATTTTTTTGGCACCAACCAATCTTTTGACAAGCCCTCAA
AGTGATCTGCTTAAGAAGTGGTTATCAGGATATGCTGATATTATTGCTGTTATTACTCTTCCAGAAGCAGCTTTTAGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTAAAAAAACAAACTAAAAATGCTCCTGAGACCTTCGTTTACCCACTTAGCG
ATTTGCAAAATCCAAGGGTCCTCAAGGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7CBK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

68.889

99.057

0.682
  comYH Streptococcus mutans UA140

68.889

99.057

0.682

Multiple sequence alignment