Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   H0513_RS01740 Genome accession   NZ_LR822023
Coordinates   311974..312873 (+) Length   299 a.a.
NCBI ID   WP_084825763.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_368     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 310628..311803 311974..312873 flank 171


Gene organization within MGE regions


Location: 310628..312873
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0513_RS01735 (STHERMO_0340) - 310628..311803 (-) 1176 WP_179972202.1 IS256-like element IS1191 family transposase -
  H0513_RS01740 (STHERMO_0341) comR 311974..312873 (+) 900 WP_084825763.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35289.82 Da        Isoelectric Point: 5.2314

>NTDB_id=1131134 H0513_RS01740 WP_084825763.1 311974..312873(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_368]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKKKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHKSFSDFLTVIDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=1131134 H0513_RS01740 WP_084825763.1 311974..312873(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_368]
TTGAACATAAAAGACAGCATTGGATTAAGAATCAAAACTGAGCGTGAACGGCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCATCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAGGTTGAGGAAATATACGAGGACTTGTTTGAACAAGTCAAAAAGAAGAGGAAGTTCTCGACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCATAAGTCCTTCTCAGACTTCTTAACAGTTATAGATAAAGCATTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(11-66)

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMG 18311

98.662

100

0.987
  comR Streptococcus thermophilus LMD-9

97.993

100

0.98
  comR Streptococcus salivarius strain HSISS4

94.649

100

0.946
  comR Streptococcus salivarius SK126

93.98

100

0.94
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.475

100

0.425
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.475

100

0.425

Multiple sequence alignment