Detailed information NTG1131093

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H0514_RS05405
• Genome accession: NZ_LR822020
• Coordinates: 1058719..1059558 (-)
• Length: 279 a.a.
• NCBI ID: WP_100262427.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_956
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1053719..1064558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0514_RS05390 (STHERMO_1235)	-	1054771..1055430 (-)	660	WP_179972928.1	response regulator transcription factor	-
H0514_RS05395 (STHERMO_1236)	-	1055466..1056290 (-)	825	WP_179972927.1	TraX family protein	-
H0514_RS05400 (STHERMO_1237)	topA	1056407..1058551 (-)	2145	WP_179973122.1	type I DNA topoisomerase	-
H0514_RS05405 (STHERMO_1239)	dprA	1058719..1059558 (-)	840	WP_100262427.1	DNA-processing protein DprA	Machinery gene
H0514_RS05410 (STHERMO_1240)	-	1059624..1060544 (-)	921	WP_100262428.1	ROK family protein	-
H0514_RS05415 (STHERMO_1241)	-	1060555..1061322 (-)	768	WP_100262429.1	ribonuclease HII	-
H0514_RS05420 (STHERMO_1242)	ylqF	1061309..1062163 (-)	855	WP_002950602.1	ribosome biogenesis GTPase YlqF	-
H0514_RS05425 (STHERMO_1243)	-	1062291..1062980 (-)	690	WP_046206437.1	XRE family transcriptional regulator	-
H0514_RS05430 (STHERMO_1244)	-	1063075..1063590 (-)	516	WP_179972925.1	transcription repressor NadR	-
H0514_RS05435 (STHERMO_1245)	-	1063614..1064141 (-)	528	WP_179972924.1	ECF transporter S component	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31257.21 Da
• Isoelectric Point: 8.6557

>NTDB_id=1131093 H0514_RS05405 WP_100262427.1 1058719..1059558(-) (dprA) [Streptococcus thermophilus isolate STH_CIRM_956]
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAVLFMEKYKNLDVKQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVHELGNAFTIVSGLARGIDTCAHMEAIKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKIRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHYLIQEGAKCITTGFDIISEFS

Nucleotide

• Length: 840 bp

>NTDB_id=1131093 H0514_RS05405 WP_100262427.1 1058719..1059558(-) (dprA) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTGACGAATTTAAACATCCTTAACATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCCGTTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAAGCAGCTTAAGGAAGATTTTCAACGTTTTCCGACCTTATCAATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTCCTCCTCTTTTATCAAGGGAATATTGATTTGCTAAGTAAACCCAAGTT
AGCAGTAGTTGGTGCCAGAAAGTGTTCTGAAACAGGAAAACAGTCTGTTCGAAAAATTGTTCATGAACTTGGGAACGCCT
TTACTATTGTAAGTGGCTTGGCGCGTGGAATTGATACTTGTGCTCACATGGAGGCCATAAAAAATAAAGGTAACACCATT
GCAGTTATCGGGACTGGGCTAGACGTATATTATCCTAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTACAGAATACGGACCGGGTGAACAGCCACTTAAATACCATTTTCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGAGTTATGGTGGTTGAAGCTAAGATTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGGAGA
GATGTTTTCGCCATACCAGGAAATATTTTAGATGGAAAATCGGATGGATGCCATTACCTCATTCAAGAGGGCGCAAAGTG
CATTACTACAGGATTTGACATCATTTCAGAGTTTTCATGA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	72.043	100	0.72
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus pneumoniae D39	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus pneumoniae R6	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.59	99.642	0.624
dprA/cilB/dalA	Streptococcus mitis SK321	62.59	99.642	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	60.432	99.642	0.602
dprA	Bacillus subtilis subsp. subtilis str. 168	49.048	75.269	0.369
dprA	Latilactobacillus sakei subsp. sakei 23K	39.768	92.832	0.369