Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   H0511_RS05325 Genome accession   NZ_LR822017
Coordinates   1025612..1026319 (-) Length   235 a.a.
NCBI ID   WP_179971935.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1020612..1031319
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS05300 (STHERMO_1176) yidA 1020962..1021771 (+) 810 WP_179971931.1 sugar-phosphatase -
  H0511_RS05305 (STHERMO_1177) - 1021773..1022987 (+) 1215 WP_179973777.1 aminoacyltransferase -
  H0511_RS05310 - 1023040..1023401 (-) 362 Protein_1004 YbaN family protein -
  H0511_RS05315 (STHERMO_1178) vicX 1023461..1024273 (-) 813 WP_179971933.1 MBL fold metallo-hydrolase Regulator
  H0511_RS05320 (STHERMO_1179) vicK 1024279..1025619 (-) 1341 WP_179971934.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H0511_RS05325 (STHERMO_1180) vicR 1025612..1026319 (-) 708 WP_179971935.1 response regulator YycF Regulator
  H0511_RS05330 (STHERMO_1182) - 1026843..1027610 (+) 768 WP_179973337.1 amino acid ABC transporter ATP-binding protein -
  H0511_RS05335 (STHERMO_1183) - 1027622..1028455 (+) 834 WP_179971937.1 transporter substrate-binding domain-containing protein -
  H0511_RS05340 (STHERMO_1184) - 1028473..1029171 (+) 699 WP_179971938.1 amino acid ABC transporter permease -
  H0511_RS05345 (STHERMO_1185) - 1029183..1029833 (+) 651 WP_179971939.1 amino acid ABC transporter permease -
  H0511_RS05350 - 1029897..1031154 (-) 1258 Protein_1012 ISL3 family transposase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27205.13 Da        Isoelectric Point: 4.8347

>NTDB_id=1130971 H0511_RS05325 WP_179971935.1 1025612..1026319(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_336]
MKKILVVDDERPISDIIKFNLTKEGYEVVTTFDGREALEQFEAEKPDLVILDLMLPELDGLEVVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEDNSNFGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1130971 H0511_RS05325 WP_179971935.1 1025612..1026319(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGACCTTTGATGGTCGTGAAGCTTTGGAACAATTTGAAGCTGAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGTCAAGGAAATCCGTAAAACGAGCCACACACCAATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTAACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACAATTGAAACTGCAGTAGAAGATAACTCTAACTTTGGCA
AGCAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAGATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

84.255

100

0.843
  micA Streptococcus pneumoniae Cp1015

78.97

99.149

0.783
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  covR Streptococcus salivarius strain HSISS4

44.444

99.574

0.443
  scnR Streptococcus mutans UA159

38.983

100

0.391

Multiple sequence alignment