Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   H0505_RS07060 Genome accession   NZ_LR822012
Coordinates   1368740..1369435 (-) Length   231 a.a.
NCBI ID   WP_022096989.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_30     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1363740..1374435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0505_RS07045 (STHERMO_1546) - 1364551..1365096 (-) 546 WP_022096992.1 GNAT family N-acetyltransferase -
  H0505_RS07050 (STHERMO_1547) - 1365162..1366424 (-) 1263 WP_022096991.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H0505_RS07055 (STHERMO_1548) - 1366510..1368750 (-) 2241 WP_179971003.1 DNA internalization-related competence protein ComEC/Rec2 -
  H0505_RS07060 (STHERMO_1549) comEA 1368740..1369435 (-) 696 WP_022096989.1 helix-hairpin-helix domain-containing protein Machinery gene
  H0505_RS07065 (STHERMO_1550) - 1369543..1370298 (-) 756 WP_002948862.1 lysophospholipid acyltransferase family protein -
  H0505_RS10270 (STHERMO_1551) - 1370498..1371031 (+) 534 WP_232085670.1 polysaccharide deacetylase family protein -
  H0505_RS09845 (STHERMO_1552) - 1370947..1371363 (+) 417 WP_311316677.1 hypothetical protein -
  H0505_RS07075 (STHERMO_1553) - 1371413..1372177 (+) 765 WP_179971004.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  H0505_RS07080 (STHERMO_1554) - 1372181..1372450 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24572.50 Da        Isoelectric Point: 4.5661

>NTDB_id=1130745 H0505_RS07060 WP_022096989.1 1368740..1369435(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_30]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKEGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1130745 H0505_RS07060 WP_022096989.1 1368740..1369435(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_30]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGAAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGTAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.701

100

0.987
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372

Multiple sequence alignment