Detailed information NTG1130616

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: H0507_RS05460
• Genome accession: NZ_LR822010
• Coordinates: 1023393..1024100 (-)
• Length: 235 a.a.
• NCBI ID: WP_011227274.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_29
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1018393..1029100

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0507_RS05435 (STHERMO_1184)	yidA	1018744..1019553 (+)	810	WP_011226081.1	sugar-phosphatase	-
H0507_RS05440 (STHERMO_1185)	-	1019555..1020769 (+)	1215	WP_011227270.1	aminoacyltransferase	-
H0507_RS05445	-	1020821..1021182 (-)	362	Protein_1004	YbaN family protein	-
H0507_RS05450 (STHERMO_1186)	vicX	1021242..1022054 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
H0507_RS05455 (STHERMO_1187)	vicK	1022060..1023400 (-)	1341	WP_011227273.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H0507_RS05460 (STHERMO_1188)	vicR	1023393..1024100 (-)	708	WP_011227274.1	response regulator YycF	Regulator
H0507_RS05465 (STHERMO_1190)	-	1024632..1025399 (+)	768	WP_179971832.1	amino acid ABC transporter ATP-binding protein	-
H0507_RS05470 (STHERMO_1191)	-	1025411..1026244 (+)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
H0507_RS05475 (STHERMO_1192)	-	1026262..1026960 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
H0507_RS05480 (STHERMO_1193)	-	1026972..1027622 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H0507_RS05485 (STHERMO_1194)	endA	1027693..1028574 (-)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
H0507_RS05490 (STHERMO_1195)	-	1028636..1028824 (-)	189	WP_011227277.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27115.09 Da
• Isoelectric Point: 5.0130

>NTDB_id=1130616 H0507_RS05460 WP_011227274.1 1023393..1024100(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_29]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEIVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1130616 H0507_RS05460 WP_011227274.1 1023393..1024100(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_29]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAATTGTCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	84.681	100	0.847
micA	Streptococcus pneumoniae Cp1015	79.399	99.149	0.787
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.136	100	0.383