Detailed information NTG1130598

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H0507_RS01470
• Genome accession: NZ_LR822010
• Coordinates: 269934..270833 (+)
• Length: 299 a.a.
• NCBI ID: WP_011226854.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_29
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 264934..275833

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0507_RS01450 (STHERMO_0291)	trkA	266070..267419 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
H0507_RS01455 (STHERMO_0293)	-	267678..268217 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
H0507_RS01460 (STHERMO_0294)	-	268529..269086 (+)	558	WP_002949523.1	ECF transporter S component	-
H0507_RS01465 (STHERMO_0295)	-	269089..269739 (+)	651	WP_011226853.1	phosphatase PAP2 family protein	-
H0507_RS01470 (STHERMO_0296)	comR	269934..270833 (+)	900	WP_011226854.1	helix-turn-helix domain-containing protein	Regulator
H0507_RS09605	-	271072..272250 (+)	1179	Protein_243	ABC transporter transmembrane domain-containing protein	-
H0507_RS01490 (STHERMO_0301)	-	272536..273104 (+)	569	Protein_244	ATP-binding cassette domain-containing protein	-
H0507_RS01495 (STHERMO_0302)	-	273212..273523 (+)	312	WP_011226857.1	DUF805 domain-containing protein	-
H0507_RS09610 (STHERMO_0303)	-	273491..273775 (-)	285	WP_231108755.1	hypothetical protein	-
H0507_RS09615 (STHERMO_0306)	-	274541..274912 (-)	372	WP_231108754.1	hypothetical protein	-
H0507_RS01505 (STHERMO_0307)	-	275317..275832 (+)	516	WP_011226861.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35317.79 Da
• Isoelectric Point: 5.1073

>NTDB_id=1130598 H0507_RS01470 WP_011226854.1 269934..270833(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_29]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=1130598 H0507_RS01470 WP_011226854.1 269934..270833(+) (comR) [Streptococcus thermophilus isolate STH_CIRM_29]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421