Detailed information NTG1130501

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: H0501_RS05430
• Genome accession: NZ_LR822008
• Coordinates: 1045670..1046377 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_18
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1040670..1051377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0501_RS05405 (STHERMO_1186)	yidA	1041021..1041830 (+)	810	WP_011226081.1	sugar-phosphatase	-
H0501_RS05410 (STHERMO_1187)	-	1041832..1043046 (+)	1215	WP_002953123.1	aminoacyltransferase	-
H0501_RS05415 (STHERMO_1188)	-	1043098..1043459 (-)	362	Protein_1022	YbaN family protein	-
H0501_RS05420 (STHERMO_1189)	vicX	1043519..1044331 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
H0501_RS05425 (STHERMO_1190)	vicK	1044337..1045677 (-)	1341	WP_084830671.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H0501_RS05430 (STHERMO_1191)	vicR	1045670..1046377 (-)	708	WP_011681206.1	response regulator YycF	Regulator
H0501_RS05435 (STHERMO_1192)	-	1046904..1047671 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
H0501_RS05440 (STHERMO_1193)	-	1047683..1048516 (+)	834	WP_179970665.1	transporter substrate-binding domain-containing protein	-
H0501_RS05445 (STHERMO_1194)	-	1048534..1049232 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
H0501_RS05450 (STHERMO_1195)	-	1049244..1049894 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
H0501_RS05455 (STHERMO_1196)	endA	1049966..1050847 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
H0501_RS05460 (STHERMO_1197)	-	1050909..1051097 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=1130501 H0501_RS05430 WP_011681206.1 1045670..1046377(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_18]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1130501 H0501_RS05430 WP_011681206.1 1045670..1046377(-) (vicR) [Streptococcus thermophilus isolate STH_CIRM_18]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387