Detailed information NTG1130502

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H0501_RS05455
• Genome accession: NZ_LR822008
• Coordinates: 1049966..1050847 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_18
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1044966..1055847

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0501_RS05430 (STHERMO_1191)	vicR	1045670..1046377 (-)	708	WP_011681206.1	response regulator YycF	Regulator
H0501_RS05435 (STHERMO_1192)	-	1046904..1047671 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
H0501_RS05440 (STHERMO_1193)	-	1047683..1048516 (+)	834	WP_179970665.1	transporter substrate-binding domain-containing protein	-
H0501_RS05445 (STHERMO_1194)	-	1048534..1049232 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
H0501_RS05450 (STHERMO_1195)	-	1049244..1049894 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
H0501_RS05455 (STHERMO_1196)	endA	1049966..1050847 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
H0501_RS05460 (STHERMO_1197)	-	1050909..1051097 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H0501_RS05465 (STHERMO_1198)	murA	1051099..1052370 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H0501_RS05470 (STHERMO_1199)	-	1052440..1052676 (-)	237	WP_002946959.1	DUF1146 family protein	-
H0501_RS05475 (STHERMO_1200)	galE	1052864..1053877 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
H0501_RS05480 (STHERMO_1201)	-	1053892..1054347 (-)	456	WP_024009932.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=1130502 H0501_RS05455 WP_011681210.1 1049966..1050847(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_18]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1130502 H0501_RS05455 WP_011681210.1 1049966..1050847(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_18]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594