Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   HKU360_RS00660 Genome accession   NZ_CP009612
Coordinates   104028..104456 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain HKU360     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99028..109456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKU360_RS00640 (HKU360_00132) - 101359..101724 (+) 366 WP_002986560.1 DUF1033 family protein -
  HKU360_RS00645 (HKU360_00133) comGA 101817..102755 (+) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  HKU360_RS00650 (HKU360_00134) comGB 102691..103725 (+) 1035 WP_223845212.1 competence type IV pilus assembly protein ComGB Machinery gene
  HKU360_RS00655 (HKU360_00135) comGC 103727..104053 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  HKU360_RS00660 (HKU360_00136) comGD 104028..104456 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  HKU360_RS00665 (HKU360_00137) comGE 104413..104697 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  HKU360_RS00670 (HKU360_00138) comGF 104690..105124 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  HKU360_RS00675 (HKU360_00139) comGG 105108..105434 (+) 327 WP_002987787.1 competence type IV pilus minor pilin ComGG -
  HKU360_RS00680 (HKU360_00140) comGH 105532..106485 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  HKU360_RS00685 (HKU360_00141) - 106544..107740 (+) 1197 WP_002987791.1 acetate kinase -
  HKU360_RS00690 - 107927..108235 (+) 309 WP_002987795.1 hypothetical protein -
  HKU360_RS00695 (HKU360_00142) proC 108318..109088 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=113018 HKU360_RS00660 WP_002986548.1 104028..104456(+) (comGD) [Streptococcus pyogenes strain HKU360]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=113018 HKU360_RS00660 WP_002986548.1 104028..104456(+) (comGD) [Streptococcus pyogenes strain HKU360]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366

Multiple sequence alignment