Detailed information NTG1129621

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: GPW69_RS10610
• Genome accession: NZ_LR738724
• Coordinates: 2187605..2188801 (+)
• Length: 398 a.a.
• NCBI ID: WP_074391311.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate 9401240
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2182605..2193801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW69_RS10840	-	2183151..2183747 (-)	597	Protein_2034	SEC10/PgrA surface exclusion domain-containing protein	-
GPW69_RS10575	-	2183760..2185010 (-)	1251	WP_074391310.1	hypothetical protein	-
GPW69_RS10580	-	2185160..2185492 (+)	333	WP_024378806.1	helix-turn-helix domain-containing protein	-
GPW69_RS10600	-	2186244..2186927 (-)	684	WP_053867304.1	YoaK family protein	-
GPW69_RS10605	rlmH	2186952..2187431 (-)	480	WP_004194528.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
GPW69_RS10610	htrA	2187605..2188801 (+)	1197	WP_074391311.1	S1C family serine protease	Regulator
GPW69_RS10615	spo0J	2188862..2189626 (+)	765	WP_074391312.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41829.81 Da
• Isoelectric Point: 4.4852

>NTDB_id=1129621 GPW69_RS10610 WP_074391311.1 2187605..2188801(+) (htrA) [Streptococcus suis isolate 9401240]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIIGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTTVAEFADSDTIKVGETTIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=1129621 GPW69_RS10610 WP_074391311.1 2187605..2188801(+) (htrA) [Streptococcus suis isolate 9401240]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTCTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCATTCTTCCAACCACAGGTTCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCATTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGAGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTACTGTTGCTGAATTTGCTGATTCCGATACAATCAAAGTTGGAGAAACTACTATCGCAATTGGTAGTCC
TCTAGGTAGTGTCTACGCCAATACAGTTACTCAAGGTATTATTTCCAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ACGGACAAACAATCTCAACCAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGAGGACCATTGATTAAT
ATCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGATCTCCAGAGCGCTCTCTACAAACATCAAATTGGTGACACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.95	99.749	0.598
htrA	Streptococcus gordonii str. Challis substr. CH1	59.494	99.246	0.59
htrA	Streptococcus pneumoniae D39	57.506	98.744	0.568
htrA	Streptococcus pneumoniae TIGR4	57.506	98.744	0.568
htrA	Streptococcus mitis NCTC 12261	57.506	98.744	0.568
htrA	Streptococcus pneumoniae R6	57.506	98.744	0.568
htrA	Streptococcus pneumoniae Rx1	57.506	98.744	0.568