Detailed information NTG1129596

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: GPW69_RS04780
• Genome accession: NZ_LR738724
• Coordinates: 959629..960471 (+)
• Length: 280 a.a.
• NCBI ID: WP_024408845.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate 9401240
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 954629..965471

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW69_RS04745	ylqF	954728..955579 (+)	852	WP_074391057.1	ribosome biogenesis GTPase YlqF	-
GPW69_RS04750	-	955566..956339 (+)	774	WP_074391056.1	ribonuclease HII	-
GPW69_RS04755	-	956342..957352 (+)	1011	WP_044679463.1	YdcF family protein	-
GPW69_RS04760	trhA	957387..958037 (-)	651	WP_044679457.1	PAQR family membrane homeostasis protein TrhA	-
GPW69_RS04765	-	958027..958473 (-)	447	WP_074391055.1	DUF1836 domain-containing protein	-
GPW69_RS04770	-	958570..958881 (-)	312	WP_074391054.1	rhodanese-like domain-containing protein	-
GPW69_RS04775	-	959011..959568 (+)	558	WP_074391053.1	sugar O-acetyltransferase	-
GPW69_RS04780	dprA	959629..960471 (+)	843	WP_024408845.1	DNA-processing protein DprA	Machinery gene
GPW69_RS04785	topA	960564..962657 (+)	2094	WP_024408846.1	type I DNA topoisomerase	-
GPW69_RS04790	rplJ	963213..963707 (+)	495	WP_002936486.1	50S ribosomal protein L10	-
GPW69_RS04795	rplL	963773..964138 (+)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
GPW69_RS04800	-	964338..964505 (+)	168	WP_032499127.1	hypothetical protein	-
GPW69_RS04805	-	964508..965326 (+)	819	WP_024401260.1	replication initiator protein A	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31220.15 Da
• Isoelectric Point: 8.8473

>NTDB_id=1129596 GPW69_RS04780 WP_024408845.1 959629..960471(+) (dprA) [Streptococcus suis isolate 9401240]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGVQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKVYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCITSGLDIISEYKF

Nucleotide

• Length: 843 bp

>NTDB_id=1129596 GPW69_RS04780 WP_024408845.1 959629..960471(+) (dprA) [Streptococcus suis isolate 9401240]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTACGTAATGTCGCTGTAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCACTCAAACAGATTTACAATCCGCCTGTACTTTTATTTTATCAAGGGGATTTAGAATTGCTGGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTGTTCAGTCAGTTCAGAAGATTATCAAGGAATTGAGTAATCGCT
TTGTCATTGTTAGTGGTTTGGCAAGAGGAATTGATACGGCTGCCCACATCGCCAGTTTGAAAAATGGAGGCCAAACCATT
GCTGTAATTGGAACAGGTTTGGATAAGGTCTATCCCAAAGAAAACAAGGACTTGCAGACCTACATTGGCAAACACCATTT
AGTATTAACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTCCCAGAACGTAACCGCATCATTGCTGGGTTGG
TAGAAGGTCTGGTAGTCTGTGAGGCAAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGGAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGGGCAAAGTG
CATCACATCAGGCTTGGACATCATTTCTGAGTATAAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70.714	100	0.707
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis SK321	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.214	100	0.632
dprA	Lactococcus lactis subsp. cremoris KW2	59.286	100	0.593
dprA	Legionella pneumophila strain ERS1305867	41.7	88.214	0.368
dprA	Bacillus subtilis subsp. subtilis str. 168	50.746	71.786	0.364