Detailed information NTG1129555

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: GPW68_RS05675
• Genome accession: NZ_LR738723
• Coordinates: 1121641..1122483 (+)
• Length: 280 a.a.
• NCBI ID: WP_009909860.1
• Uniprot ID: A0A075SDJ3
• Organism: Streptococcus suis isolate GD-0088
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1116641..1127483

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW68_RS05645	trhA	1117364..1118014 (-)	651	WP_002936498.1	PAQR family membrane homeostasis protein TrhA	-
GPW68_RS05650	-	1118004..1118555 (-)	552	WP_002936497.1	DUF1836 domain-containing protein	-
GPW68_RS05655	-	1118663..1120315 (-)	1653	WP_002936496.1	FAD-dependent oxidoreductase	-
GPW68_RS05660	-	1120312..1120635 (-)	324	WP_002936495.1	rhodanese-like domain-containing protein	-
GPW68_RS05665	-	1120754..1121014 (+)	261	WP_009909865.1	metal-sensitive transcriptional regulator	-
GPW68_RS05670	-	1121025..1121582 (+)	558	WP_009909862.1	sugar O-acetyltransferase	-
GPW68_RS05675	dprA	1121641..1122483 (+)	843	WP_009909860.1	DNA-processing protein DprA	Machinery gene
GPW68_RS05680	topA	1122576..1124669 (+)	2094	WP_013730365.1	type I DNA topoisomerase	-
GPW68_RS05685	rplJ	1125246..1125740 (+)	495	WP_002936486.1	50S ribosomal protein L10	-
GPW68_RS05690	rplL	1125806..1126171 (+)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
GPW68_RS05695	-	1126296..1127045 (+)	750	Protein_1061	HAD family hydrolase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31260.13 Da
• Isoelectric Point: 8.6529

>NTDB_id=1129555 GPW68_RS05675 WP_009909860.1 1121641..1122483(+) (dprA) [Streptococcus suis isolate GD-0088]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGVQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKIYPKENRELQTYIGKHHLVLTEYGPGTDPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide

• Length: 843 bp

>NTDB_id=1129555 GPW68_RS05675 WP_009909860.1 1121641..1122483(+) (dprA) [Streptococcus suis isolate GD-0088]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAACAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTGCGAAATGTCGCTGTAGTGTCTGAATGTAAAAATCCAGTTCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCTTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGCGTTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCCCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCCGTTATTGGAACAGGTTTGGATAAGATATATCCCAAAGAAAATAGAGAATTACAGACCTACATCGGAAAACATCATTT
GGTTCTGACTGAATATGGACCAGGTACAGACCCTCTCAAGTACCATTTCCCAGAACGCAATCGCATAATAGCTGGTTTGG
TGGAAGGATTGGTAGTCTGTGAAGCTAAGATGCGGTCTGGTAGCCTCATTACCTGTGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCCGGCTTGGACATCATTTCAGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

3D structure

• AlphaFold DB: A0A075SDJ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	69.286	100	0.693
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis SK321	63.571	100	0.636
dprA	Lactococcus lactis subsp. cremoris KW2	60.357	100	0.604
dprA	Bacillus subtilis subsp. subtilis str. 168	51.741	71.786	0.371
dprA	Legionella pneumophila strain ERS1305867	41.7	88.214	0.368