Detailed information NTG1129393

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: GPW48_RS05470
• Genome accession: NZ_LR738720
• Coordinates: 1053170..1054012 (-)
• Length: 280 a.a.
• NCBI ID: WP_012775129.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate GD-0001
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1048170..1059012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW48_RS05450	-	1048608..1049357 (-)	750	WP_011922420.1	HAD family hydrolase	-
GPW48_RS05455	rplL	1049482..1049847 (-)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
GPW48_RS05460	rplJ	1049913..1050407 (-)	495	WP_002936486.1	50S ribosomal protein L10	-
GPW48_RS05465	topA	1050984..1053077 (-)	2094	WP_074389881.1	type I DNA topoisomerase	-
GPW48_RS05470	dprA	1053170..1054012 (-)	843	WP_012775129.1	DNA-processing protein DprA	Machinery gene
GPW48_RS05475	-	1054071..1054628 (-)	558	WP_009909862.1	sugar O-acetyltransferase	-
GPW48_RS05480	-	1054639..1054899 (-)	261	WP_009909865.1	metal-sensitive transcriptional regulator	-
GPW48_RS05485	-	1055018..1055341 (+)	324	WP_002936495.1	rhodanese-like domain-containing protein	-
GPW48_RS05490	-	1055338..1056990 (+)	1653	WP_002936496.1	FAD-dependent oxidoreductase	-
GPW48_RS05495	-	1057098..1057649 (+)	552	WP_074410809.1	DUF1836 domain-containing protein	-
GPW48_RS05500	trhA	1057639..1058289 (+)	651	WP_004195686.1	PAQR family membrane homeostasis protein TrhA	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31246.14 Da
• Isoelectric Point: 8.4451

>NTDB_id=1129393 GPW48_RS05470 WP_012775129.1 1053170..1054012(-) (dprA) [Streptococcus suis isolate GD-0001]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKLKLAVVGTRNASKNGIQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide

• Length: 843 bp

>NTDB_id=1129393 GPW48_RS05470 WP_012775129.1 1053170..1054012(-) (dprA) [Streptococcus suis isolate GD-0001]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTGCGAAATGTCGCTGTAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATTAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTATCCAATCTGTTCAGAAAATTATCAAGGAATTGAGCAATCGTT
TTGTCATTGTTAGTGGTTTGGCAAGAGGAATTGATACAGCTGCCCACATCGCCAGTTTGAAAAATGGAGGCCAAACCATT
GCTGTAATCGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAAGATTTGCAGACCTATATTGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGCAATCGCATTATAGCTGGTTTGG
TGGAAGGATTGGTAGTCTGCGAGGCAAAAATGCGGTCTGGCAGCTTGATTACTTGTGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATTTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGATTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70	100	0.7
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis SK321	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.571	100	0.636
dprA	Lactococcus lactis subsp. cremoris KW2	60	100	0.6
dprA	Legionella pneumophila strain ERS1305867	42.105	88.214	0.371
dprA	Bacillus subtilis subsp. subtilis str. 168	50.746	71.786	0.364